Evidence map›Paper›PMID 35054281›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Accuracy and Clinical Relevance of Intra-Tumoral

José Guilherme Datorre, Ana Carolina de Carvalho, Mariana Bisarro Dos Reis, Monise Dos Reis, Marcus Matsushita, Florinda Santos, Denise Peixoto Guimarães, Rui Manuel Reis

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. A Duplex qPCR Assay Targeting theInternational journal of molecular sciences · 2025
    Article
  3. Highly Sensitive DNA Testing of Fusobacterium nucleatum in Colorectal Tumors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  4. IntratumoralJournal of oral microbiology · 2025
    Article
  5. Article
  6. Application ofWorld journal of gastrointestinal oncology · 2024
    Article
  7. Article
  8. Expert reviews in molecular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

José Guilherme DatorreMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784400, Brazil.ORCID 0000-0002-9682-7517
Ana Carolina de CarvalhoMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784400, Brazil.
Mariana Bisarro Dos ReisMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784400, Brazil.
Monise Dos ReisDepartment of Pathology, Barretos Cancer Hospital, Barretos 14784400, Brazil.
Marcus MatsushitaDepartment of Pathology, Barretos Cancer Hospital, Barretos 14784400, Brazil.
Florinda SantosDepartment of Medical Oncology, Barretos Cancer Hospital, Barretos 14784400, Brazil.
Denise Peixoto GuimarãesMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784400, Brazil.
Rui Manuel ReisMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784400, Brazil.ORCID 0000-0002-9639-7940
Hospital de Câncer de Barretos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of droplet digital PCR (ddPCR) to identify and quantify low-abundance targets is a significant advantage for accurately detecting potentially oncogenic bacteria.

Indexed as

biomarkerBrazilcolorectal cancerddPCRFusobacterium nucleatumprognosticqPCR

Identifiers

PMID35054281
PMCPMC8775036
OpenAlexW4206197966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.