ArticleDiagnostics (Basel, Switzerland)2022
Shear Wave Elastography and Thyroid Imaging Reporting and Data System (TIRADS) for the Risk Stratification of Thyroid Nodules-Results of a Prospective Study.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic efficiency among Eu-/C-/ACR-TIRADS and S-Detect for thyroid nodules: a systematic review and network meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Dual-mode 3D shear wave elastography with qualitative and quantitative assessment improves diagnosis of inguinal lymph node metastasis.Quantitative imaging in medicine and surgery · 2026Article
- The combination of virtual touch tissue imaging quantification (VTIQ) and American College of Radiology's Thyroid Imaging Reporting and Data System (ACR TI-RADS) improves the diagnostic efficiency for thyroid nodules with Hashimoto's thyroiditis: a retrospective study.Quantitative imaging in medicine and surgery · 2026Article
- Predictive value of real-time shear wave elastography combined with serum thyroglobulin in thyroid cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- Shear wave elastography can improve the preoperative diagnosis of parathyroid carcinoma or atypical parathyroid tumor: initial experience.BMC medical imaging · 2026Article
- [Ultrasound in secondary prevention of thyroid nodules-evidence, benefits, and limitations].HNO · 2026Review
- Multiparametric Ultrasound Features of the Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma: A Single-Center Case Series.Diagnostics (Basel, Switzerland) · 2026Article
- Evaluating shear wave elastography for differentiating lipomas from low to intermediate grade liposarcomas: is it reproducible and reliable?Skeletal radiology · 2025Article
- The Value of Multimodal Ultrasound Based on Machine Learning Algorithms in the Diagnosis of Benign and Malignant Thyroid Nodules of TI-RADS Category 4: A Single-Center Retrospective Study.Current medical imaging · 2025Article
- Enhancing diagnostic precision for thyroid C-TIRADS category 4 nodules: a hybrid deep learning and machine learning model integrating grayscale and elastographic ultrasound features.Quantitative imaging in medicine and surgery · 2025Article
- Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules-An Update.Diagnostics (Basel, Switzerland) · 2025Review
- The predictive value of the ultrasound grayscale ratio for identifying malignant thyroid nodules.Frontiers in endocrinology · 2025Article
- Interstitial Fibrosis as a Common Counterpart of Histopathological Risk Factors in Papillary Thyroid Microcarcinoma: A Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2024Article
- Evaluation of endometrial receptivity in women with unexplained infertility by shear wave elastography.Insights into imaging · 2024Article
- Differentiating benign and malignant thyroid nodules: A cross-sectional study on the comparison of diagnostic value of ultrasound elastography and fine needle aspiration biopsy.Health science reports · 2023Article
- The predictive models based on multimodality ultrasonography for the differential diagnosis of thyroid nodules smaller than 10 mm.The British journal of radiology · 2023Article
- Elastography of the thyroid nodule, cut-off points between benign and malignant lesions for strain, 2D shear wave real time and point shear wave: a correlation with pathology, ACR TIRADS and Alpha Score.Frontiers in endocrinology · 2023Article
- Viscosity Plane-Wave UltraSound (Vi PLUS) in the Evaluation of Thyroid Gland in Healthy Volunteers-A Preliminary Study.Diagnostics (Basel, Switzerland) · 2022Article
- Diagnostic performance of C-TIRADS combined with SWE for the diagnosis of thyroid nodules.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the diagnostic performance of thyroid imaging reporting and data system (TIRADS) in combination with shear wave elastography (SWE) for the assessment of thyroid nodules.
methodsA prospective study was conducted with the following inclusion criteria: preoperative B-mode ultrasound (US) including TIRADS classification (Kwak-TIRADS, EU-TIRADS), quantitative SWE and available histological results.
resultsOut of 43 patients, 61 thyroid nodules were detected; 10 nodules were found to be thyroid cancer (7 PTC, 1 FTC, 2 HüCC) and 51 were benign. According to Kwak-TIRADS the majority of benign nodules (47 out of 51, 92.2%) were classified in the low-risk- and intermediate-risk class, four nodules were classified as high-risk (7.8%). When using EU-TIRADS, the benign nodules were distributed almost equally across all risk classes, 21 (41.2%) nodules were classified in the low-risk class, 16 (31.4%) in the intermediate-risk class and 14 (27.4%) in the high-risk class. In contrast, most of the malignant nodules (eight out of ten) were classified as high-risk on EU-TIRADS. One carcinoma was classified as low-risk and one as intermediate-risk nodule. For SWE, ROC analysis showed an optimal cutoff of 18.5 kPa to distinguish malignant and benign nodules (sensitivity 80.0%, specificity 49.0%, PPV 23.5% and NPV 92.6%). The addition of elastography resulted in an increase of accuracy from 65.6% to 82.0% when using Kwak-TIRADS and from 49.2% to 72.1% when using EU-TIRADS.
conclusionOur data demonstrate that the combination of TIRADS and SWE seems to be superior for the risk stratification of thyroid nodules than each method by itself. However, verification of these results in a larger patient population is mandatory.
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