Evidence map›Paper›PMID 35054266›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Diagnostic Value of Endoscopic Ultrasound after Neoadjuvant Chemotherapy for Gastric Cancer Restaging: A Meta-Analysis of Diagnostic Test.

Victor Mihai Sacerdotianu, Bogdan Silviu Ungureanu, Sevastita Iordache, Adina Turcu-Stiolica, Antonio Facciorusso, Stefano Francesco Crinò, Adrian Saftoiu

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Victor Mihai SacerdotianuGastroenterology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Bogdan Silviu UngureanuGastroenterology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-1984-791X
Sevastita IordacheGastroenterology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Adina Turcu-StiolicaPharmacoeconomics Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-1374-276X
Antonio FacciorussoPancreas Center, Gastroenterology Unit, Department of Medicine, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-2107-2156
Stefano Francesco CrinòPancreas Center, Gastroenterology Unit, Department of Medicine, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-4560-8741
Adrian SaftoiuGastroenterology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
University of Medicine and Pharmacy of Craiova · ROUniversity of Verona · IT

Funding

Ministerul Cercetării și Inovării PN-III-P4-ID-PCCF2016-0158 (THERRES)
6 · The paper itself

Abstract

This study aimed to evaluate the diagnostic value of endoscopic ultrasound (EUS) after neoadjuvant therapy (NT) for gastric cancer restaging by meta-analysis. We conducted a systematic search of studies published on PubMed and Web of Science up to 30th August 2021. Assessing the risk of bias in the included studies was done with the QUADAS-2 tool. We used R and Review Manager 5.4.1 for calculations and statistical analysis. To evaluate the diagnostic value of EUS after NT for gastric cancer restaging, we performed a meta-analysis on six studies, with a total of 283 patients, including true-positive, true-negative, false-positive, and false-negative results for T1-T4, N0. EUS as a diagnostic test for GC patients after chemotherapy has a relatively low DOR for the T2 (3.96) and T4 stages (4.79) and a relatively high partial AUC for the T2 (0.85) and T4 (0.71) stages. Our results reveal that the pooled sensitivity for T stages after chemotherapy is rather low (29-56%), except for the T3 stage (71%). A potential limitation of our study was the small number of included studies, but no significant heterogeneity was found between them. Our meta-analysis concludes that EUS is not recommended or is still under debate for GC restaging after NT.

Indexed as

endoscopic ultrasoundgastric cancerrestaging

Identifiers

PMID35054266
PMCPMC8775115
OpenAlexW4205479781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.