Evidence map›Paper›PMID 35054225›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Pulmonary Arteriovenous Pressure Gradient and Time-Averaged Mean Velocity of Small Pulmonary Arteries Can Serve as Sensitive Biomarkers in the Diagnosis of Pulmonary Arterial Hypertension: A Preclinical Study by 4D-Flow MRI.

Ali Nahardani, Simon Leistikow, Katja Grün, Martin Krämer, Karl-Heinz Herrmann, Andrea Schrepper, Christian Jung, Sara Moradi, Paul Christian Schulze, Lars Linsen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ali NahardaniMedical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.
Simon LeistikowDepartment of Mathematics and Computer Science, Institute of Computer Science, Westfälische Wilhelms-Universität Münster, 48149 Munster, Germany.
Katja GrünDepartment of Internal Medicine I, Division of Cardiology, Angiology, Pneumology, and Intensive Medical Care, Jena University Hospital, 07747 Jena, Germany.
Martin KrämerMedical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.ORCID 0000-0002-0173-9830
Karl-Heinz HerrmannMedical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.
Andrea SchrepperDepartment of Cardiothoracic Surgery, Jena University Hospital, 07747 Jena, Germany.
Christian JungDepartment of Internal Medicine, Division of Cardiology, University Hospital Düsseldorf, 40225 Dusseldorf, Germany.ORCID 0000-0001-8325-250X
Sara MoradiHeart Center Bonn, Department of Internal Medicine II, University Hospital Bonn, 53127 Bonn, Germany.
Paul Christian SchulzeDepartment of Internal Medicine I, Division of Cardiology, Angiology, Pneumology, and Intensive Medical Care, Jena University Hospital, 07747 Jena, Germany.
Lars LinsenDepartment of Mathematics and Computer Science, Institute of Computer Science, Westfälische Wilhelms-Universität Münster, 48149 Munster, Germany.
Jürgen R ReichenbachMedical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.ORCID 0000-0002-2640-0630
Verena HoerrMedical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.
Marcus FranzDepartment of Internal Medicine I, Division of Cardiology, Angiology, Pneumology, and Intensive Medical Care, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0001-6543-4684
Jena University Hospital · DEUniversity Hospital Bonn · DEUniversity of Münster · DEDüsseldorf University Hospital · DE

Funding

Federal Ministry of Education and Research FKZ 01EO1502Open Access Publication Fund of the University of Bonn no grant number available
6 · The paper itself

Abstract

(1) Background: Pulmonary arterial hypertension (PAH) is a serious condition that is associated with many cardiopulmonary diseases. Invasive right heart catheterization (RHC) is currently the only method for the definitive diagnosis and follow-up of PAH. In this study, we sought a non-invasive hemodynamic biomarker for the diagnosis of PAH. (2) Methods: We applied prospectively respiratory and cardiac gated 4D-flow MRI at a 9.4T preclinical scanner on three different groups of Sprague Dawley rats: baseline (

Indexed as

4D-flowcardiac magnetic resonancehemodynamicspulmonary hypertensiontreatment response

Identifiers

PMID35054225
PMCPMC8774481
OpenAlexW4200061054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.