Evidence map›Paper›PMID 35054218›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Differentiation Model for Insomnia Disorder and the Respiratory Arousal Threshold Phenotype in Obstructive Sleep Apnea in the Taiwanese Population Based on Oximetry and Anthropometric Features.

Cheng-Yu Tsai, Yi-Chun Kuan, Wei-Han Hsu, Yin-Tzu Lin, Chia-Rung Hsu, Kang Lo, Wen-Hua Hsu, Arnab Majumdar, Yi-Shin Liu, Shin-Mei Hsu and 8 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Epidemiological characteristics of Chlamydial infection in hospitalized children in China: A nationwide retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Combining a wireless radar sleep monitoring device with deep machine learning techniques to assess obstructive sleep apnea severity.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Cheng-Yu TsaiDepartment of Civil and Environmental Engineering, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0002-1639-4257
Yi-Chun KuanDepartment of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Wei-Han HsuSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei 110301, Taiwan.
Yin-Tzu LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan 333423, Taiwan.
Chia-Rung HsuDepartment of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Kang LoSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Wen-Hua HsuMaster Program in Thoracic Medicine School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Arnab MajumdarDepartment of Civil and Environmental Engineering, Imperial College London, London SW7 2AZ, UK.
Yi-Shin LiuSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Shin-Mei HsuSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Shu-Chuan HoSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Wun-Hao ChengGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Shang-Yang LinSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Kang-Yun LeeDivision of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Dean WuDepartment of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.ORCID 0000-0003-0147-1640
Hsin-Chien LeeDepartment of Psychiatry, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Cheng-Jung WuSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.
Wen-Te LiuSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei 235041, Taiwan.ORCID 0000-0003-1281-8718
Taipei Medical University-Shuang Ho Hospital · TWTaipei Medical University · TWImperial College London · GBChang Gung Memorial Hospital · TW

Funding

Ministry of Science and Technology of Taiwan MOST Grant No.108-2634-F-038-003
6 · The paper itself

Abstract

Insomnia disorder (ID) and obstructive sleep apnea (OSA) with respiratory arousal threshold (ArTH) phenotypes often coexist in patients, presenting similar symptoms. However, the typical diagnosis examinations (in-laboratory polysomnography (lab-PSG) and other alternatives methods may therefore have limited differentiation capacities. Hence, this study established novel models to assist in the classification of ID and low- and high-ArTH OSA. Participants reporting insomnia as their chief complaint were enrolled. Their sleep parameters and body profile were accessed from the lab-PSG database. Based on the definition of low-ArTH OSA and ID, patients were divided into three groups, namely, the ID, low- and high-ArTH OSA groups. Various machine learning approaches, including logistic regression, k-nearest neighbors, naive Bayes, random forest (RF), and support vector machine, were trained using two types of features (Oximetry model, trained with oximetry parameters only; Combined model, trained with oximetry and anthropometric parameters). In the training stage, RF presented the highest cross-validation accuracy in both models compared with the other approaches. In the testing stage, the RF accuracy was 77.53% and 80.06% for the oximetry and combined models, respectively. The established models can be used to differentiate ID, low- and high-ArTH OSA in the population of Taiwan and those with similar craniofacial features.

Indexed as

in-laboratory polysomnographyinsomnia disorderobstructive sleep apnearandom forestrespiratory arousal threshold

Identifiers

PMID35054218
PMCPMC8774350
OpenAlexW4200099096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.