Evidence map›Paper›PMID 35054205›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Improvement of Retinal Microcirculation after Pulmonary Vein Isolation in Patients with Atrial Fibrillation-An Optical Coherence Tomography Angiography Study.

Philipp S Lange, Natasa Mihailovic, Eliane Esser, Gerrit Frommeyer, Alicia J Fischer, Niklas Bode, Dennis Höwel, Friederike Rosenberger, Nicole Eter, Lars Eckardt and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Philipp S LangeDivision of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, D-48149 Muenster, Germany.
Natasa MihailovicDepartment of Ophthalmology, Hospital Fulda, University of Marburg, Campus Fulda, D-36043 Fulda, Germany.
Eliane EsserDepartment of Ophthalmology, University of Muenster Medical Center, D-48149 Muenster, Germany.
Gerrit FrommeyerDivision of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, D-48149 Muenster, Germany.ORCID 0000-0002-1431-9886
Alicia J FischerDivision of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, D-48149 Muenster, Germany.
Niklas BodeDivision of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, D-48149 Muenster, Germany.
Dennis HöwelDivision of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, D-48149 Muenster, Germany.
Friederike RosenbergerDepartment of Ophthalmology, University of Muenster Medical Center, D-48149 Muenster, Germany.
Nicole EterDepartment of Ophthalmology, University of Muenster Medical Center, D-48149 Muenster, Germany.
Lars EckardtDivision of Electrophysiology, Department of Cardiovascular Medicine, University Hospital Muenster, D-48149 Muenster, Germany.
Larissa LahmeDepartment of Ophthalmology, University of Muenster Medical Center, D-48149 Muenster, Germany.
Maged AlnawaisehDepartment of Ophthalmology, Hospital Fulda, University of Marburg, Campus Fulda, D-36043 Fulda, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate retinal and optic nerve head (ONH) perfusion in patients with atrial fibrillation (AF) before and after catheter ablation of AF with pulmonary vein isolation (PVI).

methods34 eyes of 34 patients with AF and 35 eyes of 35 healthy subjects were included in this study. Flow density data were obtained using spectral-domain OCT-A (RTVue XR Avanti with AngioVue, Optovue, Inc, Fremont, California, USA). The data of the superficial and deep vascular layers of the macula and the ONH (radial peripapillary capillary network, RPC) before and after PVI were extracted and analysed.

resultsThe flow density in the superficial OCT-angiogram (whole en face) and the ONH (RPC) in patients with AF was significantly lower compared to healthy controls (OCT-A superficial: study group: 48.77 (45.19; 52.12)%; control group: 53.01 (50.00; 54.25)%;

conclusionsPatients with AF showed altered ocular perfusion as measured using OCTA when compared with healthy controls. Rhythm control using PVI significantly improved ocular perfusion as measured using OCT-A. Non-contact imaging using OCTA provides novel information about the central global microperfusion of patients with AF.

Indexed as

atrial fibrillationOCTAoptical coherence tomography angiographyoptic nerve head perfusionretinal perfusion

Identifiers

PMID35054205
PMCPMC8774642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.