Evidence map›Paper›PMID 35054108›Full record

ArticleJournal of clinical medicine2022

Female Sex Is a Risk Factor Associated with Long-Term Post-COVID Related-Symptoms but Not with COVID-19 Symptoms: The LONG-COVID-EXP-CM Multicenter Study.

César Fernández-de-Las-Peñas, José D Martín-Guerrero, Óscar J Pellicer-Valero, Esperanza Navarro-Pardo, Víctor Gómez-Mayordomo, María L Cuadrado, José A Arias-Navalón, Margarita Cigarán-Méndez, Valentín Hernández-Barrera, Lars Arendt-Nielsen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05736939 (Gender Differences in the Recovery Rate Following a Hybrid Pulmonary Rehabilitation Programme in Patients With Long COVID-19 Syndrome), which is not on this map. Cited by 194 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
194citing papers in PubMed, 4 pooled it
39.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05736939 completednot on this map

Gender Differences in the Recovery Rate Following a Hybrid Pulmonary Rehabilitation Programme in Patients With Long COVID-19 Syndrome

TypeobservationalSponsorNational and Kapodistrian University of AthensRan2022 to 2023Enrolled30ConditionsPost Acute COVID-19 SyndromeArmsOut-patient Pulmonary Rehabilitation
3 · Its place in the literature

Who cites it

194 citing papers in PubMed, 4 syntheses or guidelines pooled it, 319 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Long COVID Optimal Health Programme to Enhance Mental and Physical Health: A Feasibility Randomised Controlled Trial.Health expectations : an international journal of public participation in health care and health policy · 2025
    Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Lung Function Impairment after Mild SARS-CoV-2 Infection in Previously Healthy Individuals.Respiration; international review of thoracic diseases · 2026
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
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134 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

César Fernández-de-Las-PeñasDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.ORCID 0000-0003-3772-9690
José D Martín-GuerreroIntelligent Data Analysis Laboratory, Department of Electronic Engineering, ETSE (Engineering School), Universitat de València (UV), 46100 Valencia, Spain.ORCID 0000-0001-9378-0285
Óscar J Pellicer-ValeroIntelligent Data Analysis Laboratory, Department of Electronic Engineering, ETSE (Engineering School), Universitat de València (UV), 46100 Valencia, Spain.ORCID 0000-0002-0104-1029
Esperanza Navarro-PardoDepartment of Developmental and Educational Psychology, Universitat de València (UV), 46010 València, Spain.ORCID 0000-0002-9355-2909
Víctor Gómez-MayordomoDepartment of Neurology, Hospital Universitario Clínico San Carlos, 28040 Madrid, Spain.ORCID 0000-0001-9343-8439
María L CuadradoDepartment of Neurology, Hospital Universitario Clínico San Carlos, 28040 Madrid, Spain.
José A Arias-NavalónSchool of Health Sciences, Universidad Alfonso X El Sabio, 28691 Madrid, Spain.ORCID 0000-0001-5059-7667
Margarita Cigarán-MéndezDepartment of Psychology, Universidad Rey Juan Carlos (URJC), 28933 Madrid, Spain.
Valentín Hernández-BarreraDepartment of Public Health, Universidad Rey Juan Carlos (URJC), 28933 Madrid, Spain.
Lars Arendt-NielsenCNAP, Center for Sensory-Motor Interaction (SMI), Department of Health Science and Technology, Faculty of Medicine, Aalborg University, 9220 Aalborg, Denmark.
Universidad Rey Juan Carlos · ESUniversitat de València · ESAalborg University Hospital · DKHospital Clínico San Carlos · ESUniversidad Alfonso X el Sabio · ESUniversidad Complutense de Madrid · ES

Funding

Comunidad de Madrid The LONG-COVID-EXP-CMNovo Nordisk Foundation NNF21OC0067235
6 · The paper itself

Abstract

This multicenter cohort study investigated the differences between coronavirus disease 2019 (COVID-19) related symptoms and post-COVID symptoms between male and female COVID-19 survivors. Clinical and hospitalization data were collected from hospital medical records in a sample of individuals recovered from COVID-19 at five public hospitals in Spain. A predefined list of post-COVID symptoms was systematically assessed, but patients were free to report any symptom. Anxiety/depressive levels and sleep quality were also assessed. Adjusted multivariate logistic regressions were used to identify the association of sex with post-COVID related-symptoms. A total of 1969 individuals (age: 61, SD: 16 years, 46.4% women) were assessed 8.4 months after discharge. No overall significant sex differences in COVID-19 onset symptoms at hospital admission were found. Post-COVID symptoms were present in up to 60% of hospitalized COVID-19 survivors eight months after the infection. The number of post-COVID symptoms was 2.25 for females and 1.5 for males. After adjusting by all variables, female sex was associated with ≥3 post-COVID symptoms (adj OR 2.54, 95%CI 1.671-3.865,

Indexed as

COVID-19fatiguefemalepost-COVIDrisk factorssexsymptoms

Identifiers

PMID35054108
PMCPMC8778106
OpenAlexW4205140567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.