Evidence map›Paper›PMID 35054081›Full record

ArticleJournal of clinical medicine2022

Diagnostic Value of 18F-FDG PET/CT vs. Chest-Abdomen-Pelvis CT Scan in Management of Patients with Fever of Unknown Origin, Inflammation of Unknown Origin or Episodic Fever of Unknown Origin: A Comparative Multicentre Prospective Study.

Kim-Heang Ly, Nathalie Costedoat-Chalumeau, Eric Liozon, Stéphanie Dumonteil, Jean-Pierre Ducroix, Laurent Sailler, Olivier Lidove, Boris Bienvenu, Olivier Decaux, Pierre-Yves Hatron and 13 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01200771 (Impact of the PET-scan in the Diagnosis Strategy of Fever Unknown Origin or Inflammatory Syndrome in Immunocompetent Patients), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01200771 nacompletednot on this map

Impact of the PET-scan in the Diagnosis Strategy of Fever Unknown Origin or Inflammatory Syndrome in Immunocompetent Patients

TypeinterventionalSponsorUniversity Hospital, LimogesRan2008 to 2014Enrolled116ConditionsFeverArmsTEP
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. State-of-the-Art Review: Contemporary Ambulatory Approach to Adult Fever of Unknown Origin.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  2. Determinants of diagnostic yield and scan quality of [Critical care (London, England) · 2026
    Article
  3. Role ofJournal of clinical medicine · 2025
    Review
  4. Article
  5. Article
  6. What Is the Role of [Open forum infectious diseases · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 12 institutions in 1 country.

Kim-Heang LyDepartment of Internal Medicine, Limoges University Hospital, CEDEX, 87042 Limoges, France.ORCID 0000-0002-8511-903X
Nathalie Costedoat-ChalumeauAP-HP, Cochin University Hospital, Internal Medicine Department, Referral Centre for Rare Autoimmune and Systemic Diseases, 75014 Paris, France.
Eric LiozonDepartment of Internal Medicine, Limoges University Hospital, CEDEX, 87042 Limoges, France.
Stéphanie DumonteilDepartment of Internal Medicine, Limoges University Hospital, CEDEX, 87042 Limoges, France.
Jean-Pierre DucroixDepartment of Internal Medicine, Amiens University Hospital, 80054 Amiens, France.
Laurent SaillerDepartment of Internal Medicine, CHU Toulouse-Purpan, CEDEX, 31059 Toulouse, France.
Olivier LidoveDepartment of Internal Medicine, Groupe Hospitalier Diaconesses-Croix Saint-Simon, 75020 Paris, France.
Boris BienvenuDepartment of Internal Medicine, Caen University Hospital, CEDEX 9, 14033 Caen, France.
Olivier DecauxDepartment of Internal Medicine CHU de Rennes, 35000 Rennes, France.
Pierre-Yves HatronDepartment of Internal Medicine, CHU Claude Huriez, 59000 Lille, France.
Amar SmailDepartment of Internal Medicine, Amiens University Hospital, 80054 Amiens, France.
Léonardo AstudilloDepartment of Internal Medicine, CHU Toulouse-Purpan, CEDEX, 31059 Toulouse, France.
Nathalie MorelAP-HP, Cochin University Hospital, Internal Medicine Department, Referral Centre for Rare Autoimmune and Systemic Diseases, 75014 Paris, France.
Jonathan BoutemyDepartment of Internal Medicine, Caen University Hospital, CEDEX 9, 14033 Caen, France.
Antoinette PerlatDepartment of Internal Medicine CHU de Rennes, 35000 Rennes, France.ORCID 0000-0002-4985-423X
Eric DenesDepartment of Infectious Diseases, CHU Limoges, CEDEX, 87042 Limoges, France.
Marc LambertDepartment of Internal Medicine, CHU Claude Huriez, 59000 Lille, France.
Thomas PapoDepartment of Internal Medicine, Paris Diderot University, Assistance Publique-Hôpitaux de Paris, Bichat Hospital, 75018 Paris, France.
Anne CypierreDepartment of Infectious Diseases, CHU Limoges, CEDEX, 87042 Limoges, France.
Elisabeth VidalDepartment of Internal Medicine, Limoges University Hospital, CEDEX, 87042 Limoges, France.
Pierre-Marie PreuxCentre d'Epidémiologie de Biostatistique et de Méthodologie de la Recherche, Limoges University Hospital, CEDEX, 87042 Limoges, France.
Jacques MonteilDepartment of Nuclear Medicine, Limoges University Hospital, CEDEX, 87042 Limoges, France.
Anne-Laure FauchaisDepartment of Internal Medicine, Limoges University Hospital, CEDEX, 87042 Limoges, France.
Hôpital Universitaire Dupuytren · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Caen Normandie · FRCentre Hospitalier Universitaire de Limoges · FRCIC Rennes · FRHôpital Cochin · FRHôpital Rangueil · FRCentre Oscar Lambret · FRDélégation Paris 7 · FRGroupe Hospitalier Diaconesses Croix Saint-Simon · FRHôpital Dupuytren · FRUniversité de Limoges · FR

Funding

French Ministry of Health. ClinicalTrials.gov NCT01200771.
6 · The paper itself

Abstract

Fluorodesoxyglucose Positron Emission Tomography (PET/CT) has never been compared to Chest-Abdomen-Pelvis CT (CAPCT) in patients with a fever of unknown origin (FUO), inflammation of unknown origin (IUO) and episodic fever of unknown origin (EFUO) through a prospective and multicentre study. In this study, we investigated the diagnostic value of PET/CT compared to CAPCT in these patients. The trial was performed between 1 May 2008 through 28 February 2013 with 7 French University Hospital centres. Patients who fulfilled the FUO, IUO or EFUO criteria were included. Diagnostic orientation (DO), diagnostic contribution (DC) and time for diagnosis of both imaging resources were evaluated. One hundred and three patients were included with 35 FUO, 35 IUO and 33 EFUO patients. PET/CT showed both a higher DO (28.2% vs. 7.8%,

Indexed as

chest-abdomen-pelvis CTEFUOFUOIUOPET/CT

Identifiers

PMID35054081
PMCPMC8779072
OpenAlexW4205538288

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.