Evidence map›Paper›PMID 35054075›Full record

ArticleJournal of clinical medicine2022

Prevention of Periprosthetic Joint Infection in Total Hip and Knee Replacement: One European Consensus.

Enrique Gómez-Barrena, Timothy Warren, Ian Walker, Neil Jain, Nanne Kort, François Loubignac, Simon Newman, Carsten Perka, Antonio Spinarelli, Michael R Whitehouse and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Trial
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 6 countries.

Enrique Gómez-BarrenaDepartment of Orthopaedic Surgery, Hospital La Paz, Autónoma University of Madrid, 28046 Madrid, Spain.ORCID 0000-0003-1065-6137
Timothy WarrenTriducive Ltd., Tunbridge Wells TN1 1NU, UK.
Ian WalkerTriducive Ltd., Tunbridge Wells TN1 1NU, UK.
Neil JainDepartment of Orthopaedic Surgery, Pennine Acute Hospitals NHS Trust, Manchester M8 5RB, UK.
Nanne KortCortoClinics, 5482 Schijndel, The Netherlands.ORCID 0000-0001-9769-371X
François LoubignacCH Toulon, 83056 Toulon, France.ORCID 0000-0001-7418-3610
Simon NewmanGrosvenor Orthopaedics, London W1G 9QW, UK.
Carsten PerkaDepartment of Orthopaedic Surgery, Charité Hospital Universitätsmedizin, 10117 Berlin, Germany.ORCID 0000-0002-0993-581X
Antonio SpinarelliUOC Ortopedia e Traumatologia, Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Università degli Studi di Bari "Aldo Moro", 70121 Bari, Italy.
Michael R WhitehouseMusculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol BS8 1TH, UK.ORCID 0000-0003-2436-9024
Luigi ZagraIRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.
Basilio J De la TorreDepartment of Orthopaedic Surgery, Hospital Ramón y Cajal, University of Alcalá, 28034 Madrid, Spain.
Tunbridge Wells Hospital · GBAzienda Universitaria Ospedaliera Consorziale - Policlinico Bari · ITCharité - Universitätsmedizin Berlin · DEIstituto Ortopedico Galeazzi · ITPennine Acute Hospitals NHS Trust · GBToulon Var Technologies (France) · FRUniversidad Autónoma de Madrid · ESUniversidad de Alcalá · ESUniversity Hospitals Bristol NHS Foundation Trust · GBViroclinics Biosciences (Netherlands) · NL

Funding

Becton Dickinson (United Kingdom)NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol
6 · The paper itself

Abstract

Periprosthetic joint infection (PJI) is a devastating complication in total hip and knee replacement. Its prevention is key to decrease the incidence and avoid some consequences that seriously impact patients and health systems. In view of the variety of recommendations and guidelines, we decided to conduct an expert, peer-reviewed European consensus analysis about the pre-, intra-, and postoperative prevention of PJI. A multinational group of practicing orthopedic experts developed a series of 47 consensus statements in 6 main groups of intervention, and a 2-stage Delphi approach was launched with a threshold for agreement at 75% and for very high agreement at more than 90%. A total of 306 orthopedic surgeon responses were gathered from 9 countries. Consensus was reached for 42/47 statements, 31/47 of which achieved a very high consensus. Many preoperative actions gathered strong consensus, although areas like the use of alcoholic chlorhexidine or the timing of hair removal did not attain strong consensus, despite available evidence. Intra- and postoperative actions showed more variability regarding incise drapes, skin suturing techniques, and wound follow-up. This study confirms an important consensus among orthopedic surgeons across Europe in many areas well known to contribute to the prevention of PJI; however, there are still grounds for improvement.

Indexed as

perioperative PJI preventionprosthetic joint infectiontotal hip replacementtotal knee replacement

Identifiers

PMID35054075
PMCPMC8781876
OpenAlexW4205542234

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.