ReviewJournal of clinical medicine2022
Atrial Functional Tricuspid Regurgitation as a Distinct Pathophysiological and Clinical Entity: No Idiopathic Tricuspid Regurgitation Anymore.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Leaflet Morphology Is More Strongly Associated with Atrial Functional Mitral Regurgitation Severity than Annular Dilation: A Three-Dimensional Transesophageal Echocardiographic Study.Diagnostics (Basel, Switzerland) · 2026Article
- Clinical and imaging phenotypes.European heart journal supplements : journal of the European Society of Cardiology · 2026Article
- Right Ventricular Function in Patients With Significant Tricuspid Regurgitation.Reviews in cardiovascular medicine · 2026Review
- Atrial-secondary tricuspid regurgitation: a better prognosis in early stage heart failure, but not in late stage.ESC heart failure · 2025Article
- Assessing right atrial size in patients with tricuspid regurgitation: importance of the right ventricular-focused view.European heart journal. Cardiovascular Imaging · 2024Article
- Atrial secondary tricuspid regurgitation: pathophysiology, definition, diagnosis, and treatment.European heart journal · 2024Article
- Ovine tricuspid annular dynamics and three-dimensional geometry during acute atrial fibrillation.PloS one · 2024Article
- The Relationship between Tricuspid Annular Longitudinal and Sphincter-like Features of Its Function in Healthy Adults: Insights from the MAGYAR-Healthy Study.Life (Basel, Switzerland) · 2023Article
- Comparison of effective regurgitant orifice area by the PISA method and tricuspid coaptation gap measurement to identify very severe tricuspid regurgitation and stratify mortality risk.Frontiers in cardiovascular medicine · 2023Article
- Impact of severe secondary tricuspid regurgitation on rest and exercise hemodynamics of patients with heart failure and a preserved left ventricular ejection fraction.Frontiers in cardiovascular medicine · 2023Article
- Tricuspid annular and right atrial volume changes are associated in healthy adults-insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Healthy Study.Frontiers in cardiovascular medicine · 2023Article
- Prognostic Impact of Severe Atrial Functional Tricuspid Regurgitation in Atrial Fibrillation Patients.Journal of clinical medicine · 2022Article
- The Changing Complementary Role of Multimodality Imaging in Clinical Cardiology.Journal of clinical medicine · 2022Article
- The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View.Journal of cardiovascular development and disease · 2022Review
- The Heart in the Transcatheter Intervention Era: Where Are We?Journal of clinical medicine · 2022Article
- Novel Computed Tomography Variables for Assessing Tricuspid Valve Morphology: Results from the TRIMA (Tricuspid Regurgitation IMAging) Study.Journal of clinical medicine · 2022Article
- Functional Tricuspid Regurgitation: Behind the Scenes of a Long-Time Neglected Disease.Frontiers in cardiovascular medicine · 2022Review
- Reference ranges of tricuspid annulus geometry in healthy adults using a dedicated three-dimensional echocardiography software package.Frontiers in cardiovascular medicine · 2022Article
- The atrial secondary tricuspid regurgitation is associated to more favorable outcome than the ventricular phenotype.Frontiers in cardiovascular medicine · 2022Article
- State of the art: Transcatheter tricuspid valve intervention.JRSM cardiovascular diseaseReview
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional tricuspid regurgitation (FTR) is a strong and independent predictor of patient morbidity and mortality if left untreated. The development of transcatheter procedures to either repair or replace the tricuspid valve (TV) has fueled the interest in the pathophysiology, severity assessment, and clinical consequences of FTR. FTR has been considered to be secondary to tricuspid annulus (TA) dilation and leaflet tethering, associated to right ventricular (RV) dilation and/or dysfunction (the "classical", ventricular form of FTR, V-FTR) for a long time. Atrial FTR (A-FTR) has recently emerged as a distinct pathophysiological entity. A-FTR typically occurs in patients with persistent/permanent atrial fibrillation, in whom an imbalance between the TA and leaflet areas results in leaflets malcoaptation, associated with the dilation and loss of the sphincter-like function of the TA, due to right atrium enlargement and dysfunction. According to its distinct pathophysiology, A-FTR poses different needs of clinical management, and the various interventional treatment options will likely have different outcomes than in V-FTR patients. This review aims to provide an insight into the anatomy of the TV, and the distinct pathophysiology of A-FTR, which are key concepts to understanding the objectives of therapy, the choice of transcatheter TV interventions, and to properly use pre-, intra-, and post-procedural imaging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.