ArticleJournal of clinical medicine2022
Early Measurement of ROX Index in Intermediary Care Unit Is Associated with Mortality in Intubated COVID-19 Patients: A Retrospective Study.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The Use of the Rox Index to Guide High-Flow Nasal Cannula Therapy and the Need for Intubation Is Associated With Meaningful Patient Outcomes.CHEST critical care · 2026Article
- Identifying vital sign trajectories to predict 28-day mortality of critically ill elderly patients with acute respiratory distress syndrome.Respiratory research · 2024Article
- Article
- [ROX index to predict failure with low flow devices in COVID-19].Revista medica del Instituto Mexicano del Seguro Social · 2023Observational
- Evaluating the use of the respiratory-rate oxygenation index as a predictor of high-flow nasal cannula oxygen failure in COVID-19.Acute and critical care · 2023Article
- Role of prognostic scores in predicting in-hospital mortality and failure of non-invasive ventilation in adults with COVID-19.Internal and emergency medicine · 2022Article
- Observational
- The ROX index: "Propelled" by high-flow nasal cannula therapy during the COVID-19 pandemic into greater applicability in respiratory support.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2022Article
- The Respiratory Rate-Oxygenation Index predicts failure of post-extubation high-flow nasal cannula therapy in intensive care unit patients: a retrospective cohort study.Revista Brasileira de terapia intensiva · 2022Observational
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Authors and funding
10 authors.
Funding
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Abstract
COVID-19 patients often present with rapidly progressing acute hypoxemic respiratory failure, requiring orotracheal intubation with different prognostic issues. However, ICU specialists lack predictive tools to stratify these patients. We conducted a single-center cross-sectional retrospective study to evaluate if the ROX index, measured under non-invasive oxygenation support, can predict ICU mortality in a COVID-19 intubated patient cohort. This study took place in the division of intensive care at the Geneva University Hospitals (Geneva, Switzerland). We included all consecutive adult patients treated by non-invasive oxygenation support and requiring intubation for acute respiratory failure due to COVID-19 between 9 September 2020 and 30 March 2021, corresponding to the second local surge of COVID-19 cases. Baseline demographic data, comorbidities, median ROX between H0 and H8, and clinical outcomes were collected. Overall, 82 patients were intubated after failing a non-invasive oxygenation procedure. Women represented 25.6% of the whole cohort. Median age and median BMI were 70 (60-75) years and 28 (25-33), respectively. Before intubation, the median ROX between H0 and H8 was 6.3 (5.0-8.2). In a multivariate analysis, the median ROX H0-H8 was associated with ICU mortality as a protective factor with an odds ratio (95% CI) = 0.77 (0.60-0.99);
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