ArticleJournal of clinical medicine2022
Peroral Cholangioscopy-Guided Targeted Biopsy versus Conventional Endoscopic Transpapillary Forceps Biopsy for Biliary Stricture with Suspected Bile Duct Cancer.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- A novel sheath system to improve target access for preoperative mapping biopsy: A randomized trial to inform surgical planning.Surgical endoscopy · 2026Trial
- Occult hepatocellular carcinoma presenting as bile duct invasion: A case diagnosed by cholangioscopy.Endoscopy · 2026Article
- Development and ex vivo evaluation of a novel suction-based bile duct biopsy device.iGIE : innovation, investigation and insights · 2026Article
- Advances in Diagnosis and Treatment With Cholangiopancreatoscopy.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Evolving techniques to optimize ERCP-based sampling and evaluation of malignant biliary strictures.Gastroenterology report · 2026Review
- Diagnosis of Perihilar Osteoclast Giant Cell Carcinoma in an Elderly Patient: A Report of Diagnostic Challenges Over Several Attempts.ACG case reports journal · 2025Article
- Diagnostic Yield of a Novel 11-Fr Digital Cholangioscope for Indeterminate Biliary Disease Using Macroscopic-On-Site Evaluation: Prospective Comparative Study.Journal of gastroenterology and hepatology · 2025Article
- Effectiveness of cholangioscopy guided biopsy versus ERCP guided brushings in diagnosing malignant biliary strictures.Surgical endoscopy · 2025Article
- Diagnostic cholangioscopy for surgical planning of extrahepatic cholangiocarcinoma.Scientific reports · 2025Article
- Utility of a novel tapered-tip sheath system for preoperative mapping biopsy of biliary tract cancers.Endoscopy international open · 2025Article
- Management of common bile duct stones: a comprehensive review.Frontiers in surgery · 2025Review
- Accurate and safe diagnosis and treatment of neoplastic biliary lesions using a novel 9F and 11F digital single-operator cholangioscope.Endoscopy international open · 2024Article
- Article
- Cholangioscopic biopsy sample detection of bile duct invasion by hepatocellular carcinoma: an underappreciated entity.iGIE : innovation, investigation and insights · 2022Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe recent improvement of peroral cholangioscopy (POCS) maneuverability has enabled the precise, targeted biopsy of bile duct lesions under direct cholangioscopic vision. However, as only small-cup biopsy forceps can pass through the scope channel, the resulting small sample size may limit the pathological diagnosis of biopsy specimens. This study compared the diagnostic abilities of POCS-guided biopsy and conventional fluoroscopy-guided biopsy for bile duct cancer.
methodThis multicenter, retrospective cohort study included patients exhibiting bile duct stricture with suspected cholangiocarcinoma in whom POCS-guided and fluoroscopy-guided biopsies were performed in the same session. The primary endpoint was the diagnostic sensitivity for malignancy. The size and quality of the biopsy specimens were also compared.
resultA total of 59 patients were enrolled. The sensitivity of POCS-guided biopsy was similar to that of fluoroscopy-guided biopsy (54.0% and 64.0%, respectively). However, when the modalities were combined, the sensitivity increased to 80.0%. The mean specimen size from POCS-guided biopsy was significantly smaller than that from fluoroscopy-guided biopsy. The specimen quality using fluoroscopy-guided biopsy was also better than that using POCS-guided biopsy.
conclusionsThe diagnostic sensitivity of POCS-guided biopsy is still insufficient, mainly because of the limited specimen quantity and quality. Therefore, conventional fluoroscopy-guided biopsy would be helpful to improve diagnostic sensitivity.
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