Evidence map›Paper›PMID 35053984›Full record

ReviewJournal of clinical medicine2022

Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-Analysis.

Emmanuel Androulakis, Catrin Sohrabi, Alexandros Briasoulis, Constantinos Bakogiannis, Bunny Saberwal, Gerasimos Siasos, Dimitris Tousoulis, Syed Ahsan, Nikolaos Papageorgiou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 5 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Emmanuel AndroulakisCardiovascular Imaging Department, Royal Brompton & Harefield Hospital NHS Foundation Trust, London SW3 6NP, UK.ORCID 0000-0001-8843-2171
Catrin SohrabiElectrophysiology Department, Barts Heart Centre, St. Bartholomew's Hospital, London EC1A 7BE, UK.
Alexandros BriasoulisAlexandra Hospital, 80 Vasilissis Sophias Avenue, 11528 Athens, Greece.ORCID 0000-0002-5740-9670
Constantinos Bakogiannis3rd Cardiology Department, AUTH, Ippokrateion Hospital, 55642 Thessaloniki, Greece.
Bunny SaberwalElectrophysiology Department, Barts Heart Centre, St. Bartholomew's Hospital, London EC1A 7BE, UK.
Gerasimos Siasos3rd Cardiology Department, Sotiria Hospital, Athens University Medical School, 11527 Athens, Greece.
Dimitris Tousoulis1st Cardiology Department, Hippokration Hospital, Athens University Medical School, 11527 Athens, Greece.
Syed AhsanInstitute of Cardiovascular Science, University College London, London WC1E 6BT, UK.
Nikolaos PapageorgiouElectrophysiology Department, Barts Heart Centre, St. Bartholomew's Hospital, London EC1A 7BE, UK.
St Bartholomew's Hospital · GBAlexandra Hospital · GRIppokrateio General Hospital of Thessaloniki · GRSotiria General Hospital · GRSt George's, University of London · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation (CA) for atrial fibrillation (AF) has been proposed as a means of improving outcomes among patients with heart failure and reduced ejection fraction (HFrEF) who are otherwise receiving appropriate treatment. Unlike HFrEF, treatment options are more limited in patients with preserved ejection fraction (HFpEF) and the data pertaining to the management of AF in these patients are controversial. The aim of this systematic review and meta-analysis was to investigate the effects of CA on outcomes of patients with AF and HFpEF, such as functional status, post-procedural complications, hospitalization, morbidity and mortality, based on data from observational studies.

methodsWe systematically searched the electronic databases MEDLINE, PUBMED, EMBASE and the Cochrane Library for Central Register of Clinical Trials until May 2020.

resultsOverall, the pooling of our data showed that sinus rhythm was achieved long-term in 58.0% (95% CI 0.44-0.71). Long-term AF recurrence was noticed in 22.3% of patients. Admission for HF occurred in 6.2% (95% CI 0.04-0.09) whilst all-cause mortality was identified in 6.3% (95% CI 0.02-0.13).

conclusionThis meta-analysis is the first to focus on determining the benefits of a rhythm control strategy for patients with AF and HFpEF using CA, suggesting it may be worthwhile to investigate the effects of a CA rhythm control strategy as the default treatment of AF in HFpEF patients in randomized trials.

Indexed as

catheter ablationheart failure with preserved ejection fractionoutcomespharmacological therapy

Identifiers

PMID35053984
PMCPMC8779551
OpenAlexW4206499856

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.