Evidence map›Paper›PMID 35053885›Full record

ArticleFoods (Basel, Switzerland)2022

Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil.

Francesco Cairone, Stefania Cesa, Alessia Ciogli, Giancarlo Fabrizi, Antonella Goggiamani, Antonia Iazzetti, Gabriella Di Lena, Jose Sanchez Del Pulgar, Massimo Lucarini, Luca Cantò and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Francesco CaironeDepartment of Drug Chemistry and Technology, Sapienza, University of Roma, P.le A. Moro 5, 00185 Rome, Italy.ORCID 0000-0002-9618-1410
Stefania CesaDepartment of Drug Chemistry and Technology, Sapienza, University of Roma, P.le A. Moro 5, 00185 Rome, Italy.ORCID 0000-0002-8649-0017
Alessia CiogliDepartment of Drug Chemistry and Technology, Sapienza, University of Roma, P.le A. Moro 5, 00185 Rome, Italy.ORCID 0000-0002-7538-2424
Giancarlo FabriziDepartment of Drug Chemistry and Technology, Sapienza, University of Roma, P.le A. Moro 5, 00185 Rome, Italy.
Antonella GoggiamaniDepartment of Drug Chemistry and Technology, Sapienza, University of Roma, P.le A. Moro 5, 00185 Rome, Italy.
Antonia IazzettiDepartment of Drug Chemistry and Technology, Sapienza, University of Roma, P.le A. Moro 5, 00185 Rome, Italy.ORCID 0000-0002-7792-774X
Gabriella Di LenaCREA Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.ORCID 0000-0001-5325-2189
Jose Sanchez Del PulgarCREA Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Massimo LucariniCREA Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
Luca CantòDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Gokhan ZenginDepartment of Biology, Science Faculty, Selcuk University, 42130 Konya, Turkey.ORCID 0000-0001-6548-7823
Petra OndrejíčkováENVIRAL a.s., Trnavská Cesta, 920 41 Leopoldov, Slovakia.
Sapienza University of Rome · ITSelçuk University · TRUniversità Cattolica del Sacro Cuore · ITUniversity of Chieti-Pescara · IT

Funding

Bio-Based Industries Joint Undertaking 792054
6 · The paper itself

Abstract

The aim of this work was to develop innovative and sustainable extraction, concentration, and purification technologies aimed to recover target substances from corn oil, obtained as side stream product of biomass refineries. Residues of bioactive compounds such as carotenoids, phytosterols, tocopherols, and polyphenols could be extracted from this matrix and applied as ingredients for food and feeds, nutraceuticals, pharmaceuticals, and cosmetic products. These molecules are well known for their antioxidant and antiradical capacity, besides other specific biological activities, generically involved in the prevention of chronic and degenerative diseases. The project involved the development of methods for the selective extraction of these minor components, using as suitable extraction technique solid phase extraction. All the extracted and purified fractions were evaluated by NMR spectroscopic analyses and UV-Vis spectrophotometric techniques and characterized by quali-quantitative HPLC analyses. TPC (total phenolic content) and TFC (total flavonoid content) were also determined. DPPH and ABTS radical were used to evaluate radical quenching abilities. Acetylcholinesterase (AChE), amylase, glucosidase, and tyrosinase were selected as enzymes in the enzyme inhibitory assays. The obtained results showed the presence of a complex group of interesting molecules with strong potential in market applications according to circular economy principles.

Indexed as

antioxidant activitybioactive moleculescarotenoidsphenolicspost-fermentation corn oilvalorization of industrial side streams

Identifiers

PMID35053885
PMCPMC8774612
OpenAlexW4206735959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.