ReviewBrain sciences2022
Revisiting Hemispheric Asymmetry in Mood Regulation: Implications for rTMS for Major Depressive Disorder.
Review in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Subgenual anterior cingulate cortex in major depression: a systematic review and meta-analysis of MRI studies with patients and healthy controls.Translational psychiatry · 2026Pooled it
- Hemispheric asymmetries in borderline personality disorder: a systematic review.European archives of psychiatry and clinical neuroscience · 2025Pooled it
- Pooled it
- Interhemispheric Metabolic Effects of Transcranial Infrared Laser Stimulation of the Prefrontal Cortex.Human brain mapping · 2026Trial
- Efficacy and safety of repetitive transcranial magnetic stimulation in anorexia and bulimia nervosa: a systematic review and meta-analysis.Annals of general psychiatry · 2026Review
- EEG hemispheric asymmetry and behavioral responsiveness following rTMS in unresponsive wakefulness syndrome: an exploratory study.Journal of neuroengineering and rehabilitation · 2026Article
- Equivalent efficacy of left versus right hemisphere accelerated intermittent theta burst stimulation for major depressive disorder.Frontiers in psychiatry · 2026Article
- Advances in the Clinical Application of Neurostimulation in Major Depression.Advances in experimental medicine and biology · 2026Review
- Prefrontal Structural Asymmetry Mediates Body Mass Index and Treatment Response in Major Depressive Disorder.Depression and anxiety · 2026Article
- Comparative effects of intermittent theta-burst stimulation and sequential bilateral rTMS on depression and emotion regulation in major depressive disorder: a randomized controlled trial.Frontiers in neuroscience · 2026Article
- Resting-State and Task-Based Functional Connectivity Reveal Distinct mPFC and Hippocampal Network Alterations in Major Depressive Disorder.Brain sciences · 2025Article
- Altered asymmetry of amygdala volume mediates food addiction and weight gain.Journal of behavioral addictions · 2025Article
- Depression-associated reductions in putaminal volume are accompanied by a shift from matrix-like to striosome-like structural connectivity.Frontiers in psychiatry · 2025Article
- Beyond Pharmacology: A Narrative Review of Alternative Therapies for Anxiety Disorders.Diseases (Basel, Switzerland) · 2024Review
- Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression.Molecular psychiatry · 2024Article
- Article
- Behavioral lateralization in bipolar disorders: a systematic review.International journal of bipolar disorders · 2023Review
- Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression.Research square · 2023Article
- Electric field distribution predicts efficacy of accelerated intermittent theta burst stimulation for late-life depression.Frontiers in psychiatry · 2023Article
- A Single Session of Bifrontal tDCS Can Improve Facial Emotion Recognition in Major Depressive Disorder: An Exploratory Pilot Study.Biomedicines · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Hemispheric differences in emotional processing have been observed for over half a century, leading to multiple theories classifying differing roles for the right and left hemisphere in emotional processing. Conventional acceptance of these theories has had lasting clinical implications for the treatment of mood disorders. The theory that the left hemisphere is broadly associated with positively valenced emotions, while the right hemisphere is broadly associated with negatively valenced emotions, drove the initial application of repetitive transcranial magnetic stimulation (rTMS) for the treatment of major depressive disorder (MDD). Subsequent rTMS research has led to improved response rates while adhering to the same initial paradigm of administering excitatory rTMS to the left prefrontal cortex (PFC) and inhibitory rTMS to the right PFC. However, accumulating evidence points to greater similarities in emotional regulation between the hemispheres than previously theorized, with potential implications for how rTMS for MDD may be delivered and optimized in the near future. This review will catalog the range of measurement modalities that have been used to explore and describe hemispheric differences, and highlight evidence that updates and advances knowledge of TMS targeting and parameter selection. Future directions for research are proposed that may advance precision medicine and improve efficacy of TMS for MDD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.