Evidence map›Paper›PMID 35053833›Full record

ArticleBrain sciences2022

Confirmation Bias in the Course of Instructed Reinforcement Learning in Schizophrenia-Spectrum Disorders.

Dorota Frydecka, Patryk Piotrowski, Tomasz Bielawski, Edyta Pawlak, Ewa Kłosińska, Maja Krefft, Kamila Al Noaimy, Joanna Rymaszewska, Ahmed A Moustafa, Jarosław Drapała and 1 more

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dorota FrydeckaDepartment of Psychiatry, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.ORCID 0000-0001-8582-9958
Patryk PiotrowskiDepartment of Psychiatry, Division of Consultation Psychiatry and Neuroscience, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.
Tomasz BielawskiDepartment of Psychiatry, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.
Edyta PawlakDepartment of Experimental Therapy, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Weigel Street 12, 53-114 Wroclaw, Poland.ORCID 0000-0002-0386-7940
Ewa KłosińskaDay-Care Psychiatric Unit, University Clinical Hospital, Pasteur Street 10, 50-367 Wroclaw, Poland.
Maja KrefftDepartment of Psychiatry, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.
Kamila Al NoaimyDepartment of Psychiatry, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.
Joanna RymaszewskaDepartment of Psychiatry, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.
Ahmed A MoustafaSchool of Psychology, Marcs Institute for Brain and Behaviour, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia.
Jarosław DrapałaDepartment of Computer Science and Systems Engineering, Faculty of Information and Communication Technology, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego Street 27, 50-370 Wroclaw, Poland.
Błażej MisiakDepartment of Psychiatry, Division of Consultation Psychiatry and Neuroscience, Wroclaw Medical University, Pasteur Street 10, 50-367 Wroclaw, Poland.

Funding

National Science Center DEC-2013/11/D/HS6/04619
6 · The paper itself

Abstract

A large body of research attributes learning deficits in schizophrenia (SZ) to the systems involved in value representation (prefrontal cortex, PFC) and reinforcement learning (basal ganglia, BG) as well as to the compromised connectivity of these regions. In this study, we employed learning tasks hypothesized to probe the function and interaction of the PFC and BG in patients with SZ-spectrum disorders in comparison to healthy control (HC) subjects. In the Instructed Probabilistic Selection task (IPST), participants received false instruction about one of the stimuli used in the course of probabilistic learning which creates confirmation bias, whereby the instructed stimulus is overvalued in comparison to its real experienced value. The IPST was administered to 102 patients with SZ and 120 HC subjects. We have shown that SZ patients and HC subjects were equally influenced by false instruction in reinforcement learning (RL) probabilistic task (IPST) (

Indexed as

confirmation biasinstructed reinforcement learningschizophrenia

Identifiers

PMID35053833
PMCPMC8773670

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.