Evidence map›Paper›PMID 35053782›Full record

ArticleBrain sciences2021

Soluble Urokinase Plasminogen Activator Receptor Levels Correlation with Other Inflammatory Factors in Prognosis of Disability and Death in Patients with Ischemic Stroke.

Dorota Różański, Stanisław Szlufik, Ryszard Tomasiuk, Łukasz Milanowski, Monika Figura, Kamila Saramak, Piotr Myrcha, Dariusz Koziorowski

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dorota RóżańskiDepartment of Neurology, Faculty of Health Sciences, Medical University of Warsaw, 02-091 Warsaw, Poland.
Stanisław SzlufikFaculty of Medical Sciences and Health Sciences, Kazimierz Pulaski University of Technology and Humanities, 26-600 Radom, Poland.
Ryszard TomasiukFaculty of Medical Sciences and Health Sciences, Kazimierz Pulaski University of Technology and Humanities, 26-600 Radom, Poland.
Łukasz MilanowskiDepartment of Neurology, Faculty of Health Sciences, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-4197-8518
Monika FiguraDepartment of Neurology, Faculty of Health Sciences, Medical University of Warsaw, 02-091 Warsaw, Poland.
Kamila SaramakDepartment of Neurology, Faculty of Health Sciences, Medical University of Warsaw, 02-091 Warsaw, Poland.
Piotr MyrchaDepartment of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-6683-429X
Dariusz KoziorowskiDepartment of Neurology, Faculty of Health Sciences, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0001-8920-8024
Medical University of Warsaw · PLKazimierz Pułaski University of Technology and Humanities in Radom · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory biomarker elevated in cardiovascular diseases. The aim of this 3-year follow-up prospective study was to evaluate suPAR levels in patients with a first ischemic stroke in correlation with CRP, PCT, NT-proCNP and endothelin 1-21 and to investigate the impact of suPAR on the outcome. Fifty-one patients (mean age 73.7+ = 11.9 years, 26 female and 25 male) were included. Samples were collected on the first (suPAR 1), third (suPAR 3) and seventh days after stroke onset (suPAR 7). Plasma samples were analyzed using ELISA. A phone interview was conducted to collect follow-up information after 24 and 36 months (modified Rankin Scale, mRS). A positive correlation between suPAR levels and other inflammatory biomarkers (except endothelin 3) was observed. A positive correlation between suPAR 3 and mRS score at 24 months was observed

Indexed as

atherosclerosiscardiovascular diseasecarotid artery diseaseinflammationischemic strokesuPAR

Identifiers

PMID35053782
PMCPMC8774014
OpenAlexW4200069610

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.