Evidence map›Paper›PMID 35053765›Full record

ArticleBrain sciences2021

The Fornix May Play a Key Role in Korsakoff's Amnesia Secondary to Subcallosal Artery Infarction.

Masataka Hayashi, Ayataka Fujimoto, Hideo Enoki, Keiko Niimi, Chikanori Inenaga, Keishiro Sato, Kazunari Homma, Tomoya Arakawa, Tohru Okanishi

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Corpus Callosotomy: Editorial.Brain sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Masataka HayashiDepartment of Neurosurgery, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Ayataka FujimotoDepartment of Neurosurgery, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.ORCID 0000-0002-5308-2965
Hideo EnokiComprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Keiko NiimiDepartment of Rehabilitation, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Chikanori InenagaDepartment of Neurosurgery, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Keishiro SatoComprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Kazunari HommaDepartment of Neurology, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Tomoya ArakawaDepartment of Neurosurgery, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Tohru OkanishiComprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.ORCID 0000-0003-3295-2236
Seirei Hamamatsu General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubcallosal artery infarction injures the fornix and anterior corpus callosum and sometimes causes Korsakoff's amnesia. We hypothesized that Korsakoff's amnesia might be caused by fornix dysfunction rather than anterior corpus callosum dysfunction in subcallosal artery infarction.

methodsA systematic review approach was applied to search PubMed and Google Scholar for articles to compare patients who had both bilateral fornix and corpus callosum infarction due to subcallosal artery territory ischemia (vascular event group; V group) with patients who had undergone anterior corpus callosotomy (callosotomy group; C group).

resultsThe V group comprised 10 patients (mean age, 63 years; median, 69 years; standard deviation (SD), 14.5 years; 5 males, 5 females). The C group comprised 6 patients (mean age, 23.7 years; median, 20 years; SD, 7.3 years; 3 males, 3 females). Six of 10 patients (60%) with subcallosal artery infarction exhibited Korsakoff's amnesia. One patient showed neither confabulation nor amnesia. Conversely, no amnesia episodes were seen in any patients from the C group (

conclusionFornix injury, rather than anterior corpus callosum injury, might be the major cause of Korsakoff's amnesia in patients with subcallosal artery infarction.

Indexed as

aneurysmconfabulationinterventional radiology therapyKorsakoff’s amnesiamemory disturbancesubcallosal artery infarction

Identifiers

PMID35053765
PMCPMC8773842
OpenAlexW4200001956

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.