Evidence map›Paper›PMID 35053739›Full record

ArticleChildren (Basel, Switzerland)2022

Loss of Health Promoting Bacteria in the Gastrointestinal Microbiome of PICU Infants with Bronchiolitis: A Single-Center Feasibility Study.

Madeleine M Russell, Mara L Leimanis-Laurens, Sihan Bu, Gigi A Kinney, Shao Thing Teoh, Ruth-Anne L McKee, Karen Ferguson, John W Winters, Sophia Y Lunt, Jeremy W Prokop and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Madeleine M RussellDepartment of Food Science and Human Nutrition, Michigan State University, Lansing, MI 48824, USA.
Mara L Leimanis-LaurensDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-0595-4578
Sihan BuDepartment of Food Science and Human Nutrition, Michigan State University, Lansing, MI 48824, USA.
Gigi A KinneyDepartment of Food Science and Human Nutrition, Michigan State University, Lansing, MI 48824, USA.
Shao Thing TeohDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-5938-258X
Ruth-Anne L McKeePediatric Intensive Care Unit, Helen DeVos Children's Hospital, Grand Rapids, MI 49503, USA.
Karen FergusonPediatric Intensive Care Unit, Helen DeVos Children's Hospital, Grand Rapids, MI 49503, USA.ORCID 0000-0001-7152-2082
John W WintersDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.
Sophia Y LuntDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-4522-6065
Jeremy W ProkopDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.
Surender RajasekaranDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.
Sarah S ComstockDepartment of Food Science and Human Nutrition, Michigan State University, Lansing, MI 48824, USA.ORCID 0000-0003-3107-7652

Funding

Spectrum Health RI0013-18
6 · The paper itself

Abstract

The feasibility of gastrointestinal (GI) microbiome work in a pediatric intensive care unit (PICU) to determine the GI microbiota composition of infants as compared to control infants from the same hospital was investigated. In a single-site observational study at an urban quaternary care children's hospital in Western Michigan, subjects less than 6 months of age, admitted to the PICU with severe respiratory syncytial virus (RSV) bronchiolitis, were compared to similarly aged control subjects undergoing procedural sedation in the outpatient department. GI microbiome samples were collected at admission (

Indexed as

antibioticscritical caredietgut microbiomepediatricsrespiratory syncytial virusviral bronchiolitis

Identifiers

PMID35053739
PMCPMC8774632

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.