ReviewCancers2022
Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Patient-specific implants for joint-sparing reconstruction of segmental tibial and femoral defects : systematic literature review and introduction of a classification framework.Bone & joint research · 2026Pooled it
- Outcomes over 30 years after megaprosthetic reconstruction of the lower limb following tumor resection: a retrospective case series of 10 patients.Japanese journal of clinical oncology · 2026Article
- Outcomes of Megaprosthetic Reconstruction After Tumor Resection of the Distal Femur and Proximal Tibia: A Single-Center Retrospective Study of 241 Cases.Journal of clinical medicine · 2026Article
- Revision-Free Survival After MUTARS Total Knee Reconstruction in Limb Salvage Surgery: Primary Implantation Versus Conversion.Cancers · 2026Article
- Ferroptosis in orthopedic implant integration after oncologic surgery.Frontiers in oncology · 2026Review
- Evaluation of Zimmer® segmental distal femur mega-prostheses: Patient survival, surgical outcomes and functional outcome.Journal of bone oncology · 2025Article
- Management of periprosthetic proximal femoral fracture of megaprosthesis with limited residual bone stock: A case report.International journal of surgery case reports · 2025Article
- Glenohumeral Instability and Clinical Outcomes Following Proximal Humerus Resection and Megaprosthesis Implantation: A Systematic Review.Journal of clinical medicine · 2025Review
- The Survival Rate and Its Influencing Factors of Modular Endoprosthetic Replacement With Uncemented Stem for the Proximal Femur After Primary Tumor Resection.Orthopaedic surgery · 2025Article
- Revision surgery for aseptic prosthetic loosening in patients treated for knee tumors: Role of gait and imaging parameters.Journal of orthopaedics · 2025Article
- Physical Function Following Megaprosthesis Surgery in the Lower Limb-A Prospective Cohort Study of 38 Patients.Arthroplasty today · 2025Article
- Failure Modes in Orthopedic Oncologic Reconstructive Surgery: A Review of Imaging Findings and Failure Rates.Current oncology (Toronto, Ont.) · 2024Review
- Outcome of Endoprosthetic Hip Reconstruction Following Resection of Malignant Bone Tumors.Cancers · 2024Article
- Antitumoral-Embedded Biopolymeric Spheres for Implantable Devices.Pharmaceutics · 2024Article
- [Individualized surgical treatment of sarcomas of the extremities].Chirurgie (Heidelberg, Germany) · 2024Review
- Risk factors for peri-megaprosthetic joint infections in tumor surgery: A systematic review.SICOT-J · 2024Article
- Distal Humeral Replacement in Patients with Primary Bone Sarcoma: The Functional Outcome and Return to Sports.Cancers · 2023Article
- 3D-printed custom-made short stem with porous structure for fixation of massive endoprosthesis in joint-preserving reconstruction after tumor resection.Journal of orthopaedic surgery and research · 2023Article
- Function and return to sports after proximal humeral replacement in patients with primary bone sarcoma.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022Article
- Microsurgical Reconstruction in Orthopedic Tumor Resections as Part of a Multidisciplinary Surgical Approach for Sarcomas of the Extremities.Life (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Megaprosthetic reconstruction of segmental bone defects following sarcoma resection is a frequently chosen surgical approach in orthopedic oncology. While the use of megaprostheses has gained popularity over the last decades and such implants are increasingly used for metastatic reconstructions and in non-tumor cases, there still is a high risk of long-term complications leading to revision surgery. This article investigates current implant survivorship, frequency and types of complications as well as functional outcomes of upper and lower limb megaprosthetic reconstructions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.