Evidence map›Paper›PMID 35053497›Full record

ArticleCancers2022

Hyperpolarized

Stephan Ursprung, Ramona Woitek, Mary A McLean, Andrew N Priest, Mireia Crispin-Ortuzar, Cara R Brodie, Andrew B Gill, Marcel Gehrung, Lucian Beer, Antony C P Riddick and 23 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. A Static Phantom for Harmonization of Hyperpolarized [1-Magnetic resonance in medicine · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  19. Theranostics · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 2 institutions in 1 country.

Stephan UrsprungCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-2476-178X
Ramona WoitekCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Mary A McLeanCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Andrew N PriestDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-9771-4290
Mireia Crispin-OrtuzarCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Cara R BrodieCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Andrew B GillCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-9287-9563
Marcel GehrungCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Lucian BeerCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-4388-7580
Antony C P RiddickDepartment of Urology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Johanna Field-RaynerCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
James T GristDepartment of Radiology, University of Cambridge, Cambridge CB2 0QQ, UK.
Surrin S DeenCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-6206-7337
Frank RiemerCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-3805-5221
Joshua D KaggieCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0001-6706-3442
Fulvio ZaccagnaCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0001-6838-9532
Joao A G DuarteCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Matthew J LockeCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Amy FraryCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Tevita F AhoDepartment of Urology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
James N ArmitageDepartment of Urology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Ruth CaseyDepartment of Endocrinology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Iosif A MendichovszkyCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Sarah J WelshCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0001-5690-2677
Tristan BarrettCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Martin J GravesDepartment of Radiology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Tim EisenCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0001-9663-4873
Thomas J MitchellCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Anne Y WarrenCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Kevin M BrindleCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3883-6287
Evis SalaCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.
Grant D StewartCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-3188-9140
Ferdia A GallagherCancer Research UK Cambridge Centre, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-4784-5230
University of Cambridge · GBCambridge University Hospitals NHS Foundation Trust · GB

Funding

Austrian Science Fund FWF J 4025Cancer Research UK 16465Cancer Research UK 16628Cancer Research UK 27150Cancer Research UK 27176Cancer Research UK C19212/A16628Cancer Research UK C19212/A27150Cancer Research UK C19212/A911376Cancer Research UK C9685/A25117Medical Research Council MR/T024097/1Wellcome Trust 095962
6 · The paper itself

Abstract

Differentiating aggressive clear cell renal cell carcinoma (ccRCC) from indolent lesions is challenging using conventional imaging. This work prospectively compared the metabolic imaging phenotype of renal tumors using carbon-13 MRI following injection of hyperpolarized [1-

Indexed as

cancer metabolismhyperpolarized 13C magnetic resonance imagingmonocarboxylate transporterrenal cell carcinoma

Identifiers

PMID35053497
PMCPMC8773685
OpenAlexW4206333456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.