Evidence map›Paper›PMID 35053476›Full record

ArticleCancers2022

Nuclear Localization of BRAF

Mourad Zerfaoui, Eman Toraih, Emmanuelle Ruiz, Youssef Errami, Abdallah S Attia, Moroz Krzysztof, Zakaria Y Abd Elmageed, Emad Kandil

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mourad ZerfaouiDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Eman ToraihDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0001-9267-3787
Emmanuelle RuizDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Youssef ErramiDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0002-0432-4331
Abdallah S AttiaDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Moroz KrzysztofDepartment of Pathology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Zakaria Y Abd ElmageedDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.ORCID 0000-0003-4031-0348
Emad KandilDepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Tulane University · US

Funding

Carol Lavin Bernick Grant 631465Tulane University Health Sciences Center (PI) 2021-2022
6 · The paper itself

Abstract

backgroundPreviously, we have demonstrated that nuclear BRAF

methodsProteomics analysis was performed to identify the interacting partner(s) of nuclear BRAF

resultsProteomics results showed that HMOX-1 protein expression was 10-fold higher in resistant A375R cells compared to parental counterpart cells. In vitro and in vivo results illustrate that nuclear BRAF

conclusionsOur results highlight a previously unknown mechanism in which the nuclear BRAF

Indexed as

aggressivenessHMOX-1melanomanuclear BRAFV600Epoor prognosisvemurafenib resistance

Identifiers

PMID35053476
PMCPMC8773521
OpenAlexW4205350890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.