Evidence map›Paper›PMID 35053393›Full record

ArticleCells2022

Generation and Application of Inducible Chimeric RNA

Yichen Luo, Liang Du, Zhimeng Yao, Fan Liu, Kai Li, Feifei Li, Jianlin Zhu, Robert P Coppes, Dianzheng Zhang, Yunlong Pan and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Yichen LuoInstitute of Precision Cancer Medicine and Pathology, School of Medicine and Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Liang DuDepartment of Biomedical Sciences of Cells & Systems, Section Molecular Cell Biology and Radiation Oncology, University Medical Center Groningen, University of Groningen, 9700 AD Groningen, The Netherlands.
Zhimeng YaoDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Fan LiuInstitute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.
Kai LiInstitute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.
Feifei LiDepartment of Oncology, People's Hospital of Leshan, Leshan 614099, China.
Jianlin ZhuDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Robert P CoppesDepartment of Biomedical Sciences of Cells & Systems, Section Molecular Cell Biology and Radiation Oncology, University Medical Center Groningen, University of Groningen, 9700 AD Groningen, The Netherlands.ORCID 0000-0001-5503-1064
Dianzheng ZhangDepartment of Bio-Medical Sciences, Philadelphia College of Osteopathic Medicine, 4170 City Avenue, Philadelphia, PA 19131, USA.ORCID 0000-0001-7732-9689
Yunlong PanDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Shegan GaoHenan Key Laboratory of Cancer Epigenetics, College of Clinical Medicine, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, China.
Hao ZhangDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-2860-5912
Jinan University · CNFirst Affiliated Hospital of Jinan University · CNUniversity Medical Center Groningen · NLFirst Affiliated Hospital of Henan University of Science and Technology · CNPhiladelphia College of Osteopathic Medicine · US

Funding

National Natural Science Foundation of China 82072683, 81773087, 81071736, 81572876 and 30973508Natural Science Foundation of Guangdong Province of China 2021A1515012522 and 9151018004000000Science and Technology Planning Project of Guangdong Province of China 2019A030317024Special Project on the Integration of Industry, Education and Research of Guangdong Province 2011A090100024
6 · The paper itself

Abstract

Chimeric RNAs (chiRNAs) play many previously unrecognized roles in different diseases including cancer. They can not only be used as biomarkers for diagnosis and prognosis of various diseases but also serve as potential therapeutic targets. In order to better understand the roles of chiRNAs in pathogenesis, we inserted human sequences into mouse genome and established a knockin mouse model of the tamoxifen-inducible expression of

Indexed as

Gene Knock-In Techniques4-Nitroquinoline-1-oxideAnimalsBody WeightCarcinogensDisease Models, AnimalEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFemaleGenotypeMiceMice, Inbred C57BLMouse Embryonic Stem CellsQuinolonesRNA, AntisenseTamoxifen4-Nitroquinoline-1-oxide4-nitroquinolone-1-oxideCarcinogensQuinolonesRNA, AntisenseTamoxifenA-PaschiRNAcancerfusion RNAgenetically engineered mouse modelknockin mousetranscription-induced chimeric RNA

Identifiers

PMID35053393
PMCPMC8773765
OpenAlexW4206352397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.