Evidence map›Paper›PMID 35053365›Full record

ReviewCells2022

Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible.

Thinzar M Lwin, Michael A Turner, Siamak Amirfakhri, Hiroto Nishino, Robert M Hoffman, Michael Bouvet

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Thinzar M LwinDepartment of Surgery, University of California San Diego, San Diego, CA 92093, USA.
Michael A TurnerDepartment of Surgery, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0001-8949-3136
Siamak AmirfakhriDepartment of Surgery, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0002-5534-1043
Hiroto NishinoDepartment of Surgery, University of California San Diego, San Diego, CA 92093, USA.
Robert M HoffmanDepartment of Surgery, University of California San Diego, San Diego, CA 92093, USA.
Michael BouvetDepartment of Surgery, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0002-0086-2159
University of California San Diego · US

Funding

UCSD Cancer Center Training Program in Drug DevelopmentT32CA121938 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Michael Bouvet, Dwayne G. Stupack · 2006 to 2026
$10.3M
NCI NIH HHS T32 CA121938
6 · The paper itself

Abstract

Colorectal cancer (CRC) is a common cause of cancer and cancer-related death. Surgery is the only curative modality. Fluorescence-enhanced visualization of CRC with targeted fluorescent probes that can delineate boundaries and target tumor-specific biomarkers can increase rates of curative resection. Approaches to enhancing visualization of the tumor-to-normal tissue interface are active areas of investigation. Nonspecific dyes are the most-used approach, but tumor-specific targeting agents are progressing in clinical trials. The present narrative review describes the principles of fluorescence targeting of CRC for diagnosis and fluorescence-guided surgery with molecular biomarkers for preclinical or clinical evaluation.

Indexed as

Molecular Targeted TherapyAnimalsBiomarkers, TumorColonic NeoplasmsFluorescenceFluorescent DyesHumansBiomarkers, TumorFluorescent Dyesfluorescence-guided surgeryfluorescent dyestumor-specific antibodiestumor-specific labeling

Identifiers

PMID35053365
PMCPMC8773892
OpenAlexW4206592100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.