Evidence map›Paper›PMID 35053171›Full record

ReviewBiomolecules2021

Automatic Activity Arising in Cardiac Muscle Sleeves of the Pulmonary Vein.

Pierre Bredeloux, Come Pasqualin, Romain Bordy, Veronique Maupoil, Ian Findlay

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Animal and cellular models of atrial fibrillation: a review.Frontiers in cardiovascular medicine · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Preferential Expression of CaBiomolecules · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pierre BredelouxEA4245, Transplantation, Immunologie et Inflammation, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Université de Tours, 37200 Tours, France.ORCID 0000-0003-0905-0680
Come PasqualinEA4245, Transplantation, Immunologie et Inflammation, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Université de Tours, 37200 Tours, France.ORCID 0000-0001-8625-1617
Romain BordyEA4245, Transplantation, Immunologie et Inflammation, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Université de Tours, 37200 Tours, France.ORCID 0000-0002-2972-688X
Veronique MaupoilEA4245, Transplantation, Immunologie et Inflammation, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Université de Tours, 37200 Tours, France.
Ian FindlayLaboratoire de Pharmacologie, Faculté de Pharmacie, Université de Tours, 37200 Tours, France.
Université de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic activity in the pulmonary vein cardiac muscle sleeves can both induce and maintain human atrial fibrillation. A central issue in any study of the pulmonary veins is their difference from the left atrial cardiac muscle. Here, we attempt to summarize the physiological phenomena underlying the occurrence of ectopic electrical activity in animal pulmonary veins. We emphasize that the activation of multiple signaling pathways influencing not only myocyte electrophysiology but also the means of excitation-contraction coupling may be required for the initiation of triggered or automatic activity. We also gather information regarding not only the large-scale structure of cardiac muscle sleeves but also recent studies suggesting that cellular heterogeneity may contribute to the generation of arrythmogenic phenomena and to the distinction between pulmonary vein and left atrial heart muscle.

Indexed as

Atrial FibrillationPulmonary VeinsAnimalsHeart AtriaMyocardiumautomatic activitycardiomyocytescatecholaminepulmonary veins

Identifiers

PMID35053171
PMCPMC8773798
OpenAlexW4200215631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.