ArticleAntibiotics (Basel, Switzerland)2022
Effect of Cephalosporin Treatment on the Microbiota and Antibiotic Resistance Genes in Feces of Dairy Cows with Clinical Mastitis.
Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 52 citations in OpenAlex.
- Probiotics as Sustainable Alternatives to Mitigate Antibiotic Resistance in Bovine Mastitis Management.Probiotics and antimicrobial proteins · 2026Review
- Impact of ceftiofur administration andmSystems · 2026Article
- Process optimization of compound fermented traditional Chinese medicine and its feeding effect on dairy cows.AMB Express · 2026Article
- Assessing the Impacts of Dairy Farm Antimicrobial Use on the Bovine Fecal Microbiome.Animals : an open access journal from MDPI · 2025Article
- Impact of Parenteral Ceftiofur on Developmental Dynamics of Early Life Fecal Microbiota and Antibiotic Resistome in Neonatal Lambs.Antibiotics (Basel, Switzerland) · 2025Article
- Antibiotic Resistance in Lactic Acid Bacteria from Dairy Products in Northern Italy.Antibiotics (Basel, Switzerland) · 2025Article
- Effects of dietary zinc on the gut microbiome and resistome of the gestating cow and neonatal calf.Animal microbiome · 2024Article
- Pharmacological composition based on bacteriocinnisin in experimentsOpen veterinary journal · 2024Article
- Confronting the complexities of antimicrobial management for Staphyloccous aureus causing bovine mastitis: an innovative paradigm.Irish veterinary journal · 2024Review
- Effects of EnterotoxigenicMicroorganisms · 2023Article
- Dilution Reduces Sample Matrix Effects for Rapid, Direct, and Miniaturised Phenotypic Antibiotic Susceptibility Tests for Bovine Mastitis.Antibiotics (Basel, Switzerland) · 2023Article
- The 16S rDNA high-throughput sequencing correlation analysis of milk and gut microbial communities in mastitis Holstein cows.BMC microbiology · 2023Article
- Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur.Veterinary research · 2023Article
- The Characterization and Beta-Lactam Resistance of Staphylococcal Community Recovered from Raw Bovine Milk.Antibiotics (Basel, Switzerland) · 2023Article
- Short-Term Impact of Oxytetracycline Administration on the Fecal Microbiome, Resistome and Virulome of Grazing Cattle.Antibiotics (Basel, Switzerland) · 2023Article
- The effects of antibiotics and illness on gut microbial composition in the fawn-footed mosaic-tailed rat (Melomys cervinipes).PloS one · 2023Article
- HMOX1 Promotes Ferroptosis in Mammary Epithelial Cells via FTH1 and Is Involved in the Development of Clinical Mastitis in Dairy Cows.Antioxidants (Basel, Switzerland) · 2022Article
- Intestinal Exposure to Ceftiofur and Cefquinome after Intramuscular Treatment and the Impact of Ceftiofur on the Pig Fecal Microbiome and Resistome.Antibiotics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Antibiotics are frequently used to treat dairy cows with mastitis. However, the potential effects of β-lactam antibiotics, such as cephalosporins, on the fecal microbiome is unknown. The objective was to investigate the effects of ceftiofur and cefquinome on the fecal microbiota and antibiotic resistance genes of dairy cows with mastitis. The fecal samples were collected from 8 dairy cows at the following periods: the start day (Day 0), medication (Days 1, 2, and 3), withdrawal (Days 4, 6, 7, and 8), and recovery (Days 9, 11, 13, and 15). 16S rRNA gene sequencing was applied to explore the changes in microbiota, and qPCR was used to investigate the antibiotic resistance genes. The cephalosporin treatment significantly decreased the microbial diversity and richness, indicated by the decreased Shannon and Chao 1 indexes, respectively (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.