Evidence map›Paper›PMID 35052982›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Management of Children Admitted to Hospitals across Bangladesh with Suspected or Confirmed COVID-19 and the Implications for the Future: A Nationwide Cross-Sectional Study.

Kona Chowdhury, Mainul Haque, Nadia Nusrat, Nihad Adnan, Salequl Islam, Afzalunnessa Binte Lutfor, Dilara Begum, Arif Rabbany, Enamul Karim, Abdul Malek and 28 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  19. Awareness and acceptance of COVID-19 vaccines and associated factors among pharmacy students in Zambia.Malawi medical journal : the journal of Medical Association of Malawi · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Kona ChowdhuryDepartment of Paediatrics, Gonoshasthaya Samaj Vittik Medical College and Hospital, Savar, Dhaka 1344, Bangladesh.ORCID 0000-0002-3836-1691
Mainul HaqueUnit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kem Perdana Sungai Besi, Kuala Lumpur 57000, Malaysia.ORCID 0000-0002-6124-7993
Nadia NusratDepartment of Paediatrics, Delta Medical College and Hospital, 26/2, Principal Abul Kashem Road, Mirpur-1, Dhaka 1216, Bangladesh.ORCID 0000-0003-0133-0303
Nihad AdnanDepartment of Microbiology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.ORCID 0000-0002-4999-4793
Salequl IslamDepartment of Microbiology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.ORCID 0000-0001-6131-4132
Afzalunnessa Binte LutforDepartment of Microbiology, Ad-Din Women's Medical College, 2 Boro Mogbazar, Dhaka 1217, Bangladesh.ORCID 0000-0002-0176-8746
Dilara BegumDepatment of Paediatrics, Dhaka Medical College Hospital, 100 Ramna Central Shaheed Minar Area, Bakshi Bazar, Dhaka 1000, Bangladesh.ORCID 0000-0002-8165-4203
Arif RabbanyDepartment of Paediatrics, Mymensnigh Medical College Hospital, Dhaka-Mymensingh Road, Mymensingh Sadar, Mymensingh 2200, Bangladesh.ORCID 0000-0001-5037-6346
Enamul KarimDepartment of Paediatrics, US-Bangla Medical College, Kornogop, Tarabo, Rupganj, Narayangonj 1460, Bangladesh.ORCID 0000-0002-3263-1988
Abdul MalekDepartment of Pediatrics, Green Life Medical College Hospital, Dhaka 1205, Bangladesh.ORCID 0000-0001-5211-6433
Nasim JahanDepartment of Pediatrics, Asgar Ali Hospital, Distillary Road, Ganderia, Dhaka 1204, Bangladesh.ORCID 0000-0001-7349-3596
Jesmine AkterDepartment of Pediatrics, Bangladesh Specialized Hospital, Mirpur Road, Dhaka 1207, Bangladesh.ORCID 0000-0001-8155-3026
Sumala AshrafDepartment of Paediatrics, Holy Family Red Crescent Medical College Hospital, 1-Eskaton Garden Road, Dhaka 1000, Bangladesh.ORCID 0000-0002-9398-3151
Mohammad Nazmul HasanDepartment Paediatric Surgery, Cumilla Medical College Hospital, Cumilla 3500, Bangladesh.ORCID 0000-0002-2448-5589
Mahmuda HassanDepartment of Paediatrics, Ad-din Women's Medical College, 2 Boro Mogbazar, Dhaka 1217, Bangladesh.ORCID 0000-0001-9935-3460
Najnin AkhterDepartment of Pediatrics, Cumilla Medical College Hospital, Cumilla 3500, Bangladesh.ORCID 0000-0003-2072-8448
Monika MazumderDepartment of Pediatrics, Rangpur Medical College, Rangpur 5400, Bangladesh.
Nazmus SihanDepartment of Pediatrics, Cumilla Medical College Hospital, Cumilla 3500, Bangladesh.ORCID 0000-0001-6952-6973
Nurun NaherDepartment of Pediatrics, Evercare Hospital, Plot-81, Block-E, Bashundhara Residential Area, Dhaka 1229, Bangladesh.ORCID 0000-0001-5953-6561
Shaheen AkterDepartment of Pediatrics, Enam Medical College and Hospital, Savar, Dhaka 1340, Bangladesh.ORCID 0000-0001-6566-2468
Sifat Uz ZamanDepartment of Microbiology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh.ORCID 0000-0001-6061-2488
Tanjina ChowdhuryDepartment of Pediatrics, Sylhet M.A.G. Osmani Medical College Hospital, Medical College Road, Kajolshah, Sylhet 3100, Bangladesh.ORCID 0000-0001-8119-5898
Jebun NesaDepartment of Paediatrics, Center for Women and Child Health, Savar, Dhaka 1349, Bangladesh.ORCID 0000-0002-4683-0689
Susmita BiswasDepartment of Paediatrics, Chattogram Medical College Hospital, Panchlaish, Chattogram 4203, Bangladesh.ORCID 0000-0003-3561-7134
Mohammod Didarul IslamDepartment of Paediatrics, Shaheed Syed Nazrul Islam Medical College, Kishorganj 2300, Bangladesh.ORCID 0000-0002-2857-6912
Al Mamun HossainDepartment of Paediatrics, Satkhira Medical College Hospital, Baka, Satkhira 9400, Bangladesh.ORCID 0000-0003-4743-8037
Habibur RahmanDepartment of Paediatrics, Meherpur District Hospital, Meherpur 7100, Bangladesh.ORCID 0000-0001-6969-3683
Palash Kumar BiswasDepartment of Paediatrics, Jashore Medical College Hospital, Jessore 7400, Bangladesh.ORCID 0000-0002-2607-445X
Mohammed ShaheenDepartment of Paediatrics, Chattogram Medical College Hospital, Panchlaish, Chattogram 4203, Bangladesh.ORCID 0000-0002-7578-4482
Farah ChowdhuryDepartment of Paediatrics, Chattogram Ma Shishu Hospital Medical College, Chattogram 4100, Bangladesh.ORCID 0000-0001-8425-8882
Santosh KumarDepartment of Periodontology and Implantology, Karnavati University, Gandhinagar 382422, India.ORCID 0000-0002-5117-7872
Amanj KurdiStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK.ORCID 0000-0001-5036-1988
Zia Ul MustafaDepartment of Pharmacy Services, District Headquarter (DHQ) Hospital, Pakpattan 57400, Pakistan.ORCID 0000-0002-8109-4859
Natalie SchellackDepartment of Pharmacology, Faculty of Health Sciences, University of Pretoria, Pretoria 0007, South Africa.ORCID 0000-0001-9690-6285
Marshall GowereDepartment of Pharmacology, Faculty of Health Sciences, University of Pretoria, Pretoria 0007, South Africa.ORCID 0000-0003-2154-3023
Johanna C MeyerDivision of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-0462-5713
Sylvia OpangaDepartment of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, Nairobi 00202, Kenya.
Brian GodmanStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK.ORCID 0000-0001-6539-6972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an increasing focus on researching children admitted to hospital with new variants of COVID-19, combined with concerns with hyperinflammatory syndromes and the overuse of antimicrobials. Paediatric guidelines have been produced in Bangladesh to improve their care. Consequently, the objective is to document the management of children with COVID-19 among 24 hospitals in Bangladesh. Key outcome measures included the percentage prescribed different antimicrobials, adherence to paediatric guidelines and mortality rates using purposely developed report forms. The majority of 146 admitted children were aged 5 years or under (62.3%) and were boys (58.9%). Reasons for admission included fever, respiratory distress and coughing; 86.3% were prescribed antibiotics, typically parenterally, on the WHO 'Watch' list, and empirically (98.4%). There were no differences in antibiotic use whether hospitals followed paediatric guidance or not. There was no prescribing of antimalarials and limited prescribing of antivirals (5.5% of children) and antiparasitic medicines (0.7%). The majority of children (92.5%) made a full recovery. It was encouraging to see the low hospitalisation rates and limited use of antimalarials, antivirals and antiparasitic medicines. However, the high empiric use of antibiotics, alongside limited switching to oral formulations, is a concern that can be addressed by instigating the appropriate programmes.

Indexed as

antibioticsantimicrobial stewardship programsBangladeshchildrenCOVID-19guidelineshospitalsoutcomes

Identifiers

PMID35052982
PMCPMC8772946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.