Evidence map›Paper›PMID 35052977›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Effect of Different Piperacillin-Tazobactam Dosage Regimens on Synergy of the Combination with Tobramycin against

Jessica R Tait, Hajira Bilal, Kate E Rogers, Yinzhi Lang, Tae-Hwan Kim, Jieqiang Zhou, Steven C Wallis, Jürgen B Bulitta, Carl M J Kirkpatrick, David L Paterson and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 4 countries.

Jessica R TaitDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Hajira BilalCentre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Kate E RogersDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Yinzhi LangDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, FL 32827, USA.
Tae-Hwan KimCollege of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Korea.
Jieqiang ZhouDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, FL 32827, USA.
Steven C WallisThe University of Queensland Center for Clinical Research, The University of Queensland, Brisbane, QLD 4029, Australia.
Jürgen B BulittaDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Orlando, FL 32827, USA.ORCID 0000-0001-7352-3097
Carl M J KirkpatrickCentre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
David L PatersonThe University of Queensland Center for Clinical Research, The University of Queensland, Brisbane, QLD 4029, Australia.
Jeffrey LipmanThe University of Queensland Center for Clinical Research, The University of Queensland, Brisbane, QLD 4029, Australia.ORCID 0000-0002-5965-9876
Phillip J BergenCentre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.ORCID 0000-0001-5671-9880
Jason A RobertsThe University of Queensland Center for Clinical Research, The University of Queensland, Brisbane, QLD 4029, Australia.ORCID 0000-0001-6218-435X
Roger L NationDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Cornelia B LandersdorferDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.ORCID 0000-0003-0928-4743
Monash University · AUThe University of Queensland · AUUniversity of Florida · USDaegu Catholic University · KR

Funding

National Health and Medical Research Council GNT1099452National Health and Medical Research Council GNT1159579National Health and Medical Research Council GNT1184428
6 · The paper itself

Abstract

We evaluated piperacillin-tazobactam and tobramycin regimens against

Indexed as

dynamic infection modelpharmacodynamicspharmacokineticsPseudomonas aeruginosa

Identifiers

PMID35052977
PMCPMC8772788
OpenAlexW4206191704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.