Evidence map›Paper›PMID 35052920›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Antibiotic Prophylaxis for Surgical Site Infection in General Surgery: Oncological Treatments and HIPEC.

Carlo Vallicelli, Federico Coccolini, Massimo Sartelli, Luca Ansaloni, Simona Bui, Fausto Catena

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Carlo VallicelliGeneral, Emergency and Trauma Surgery Department, Bufalini Hospital, 47521 Cesena, Italy.ORCID 0000-0002-9523-1324
Federico CoccoliniGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, 56124 Pisa, Italy.
Massimo SartelliDepartment of Surgery, Macerata Hospital, 62100 Macerata, Italy.
Luca AnsaloniDepartment of General and Emergency Surgery, Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0001-6427-0307
Simona BuiDepartment of Clinical Oncology, Maggiore Hospital, 43126 Parma, Italy.
Fausto CatenaGeneral, Emergency and Trauma Surgery Department, Bufalini Hospital, 47521 Cesena, Italy.
Ospedale “M. Bufalini” di Cesena · ITAzienda Ospedaliera Universitaria Pisana · ITOspedale di MacerataOspedale Maggiore · ITPoliclinico San Matteo Fondazione · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The procedure of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a combined surgical and oncological treatment for peritoneal carcinomatosis of various origins. Antibiotic prophylaxis is usually center-related and should be discussed together with the infectious disease specialist, taking into account the advanced oncologic condition of the patient, the complexity of surgery-often requiring multiorgan resections-and the risk of post-HIPEC neutropenia. The incidence of surgical site infection (SSI) after CRS and HIPEC ranges between 11 and 46%. These patients are also at high risk of postoperative abdominal infections and septic complications, and a bacterial translocation during HIPEC has been hypothesized. Many authors have proposed aggressive screening protocols and a high intra and postoperative alert, in order to minimize and promptly identify all possible infectious complications following CRS and HIPEC.

Indexed as

antibiotic prophylaxisHIPECsurgical oncologysurgical site infection

Identifiers

PMID35052920
PMCPMC8773423
OpenAlexW4206302816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.