ArticleAntibiotics (Basel, Switzerland)2021
Antibiotic Prescribing Patterns in Paediatric Primary Care in Italy: Findings from 2012-2018.
Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Pediatric stewardship in Italy: a necessity, not an option - a National Multi-Society Expert Consensus on Antimicrobial and Diagnostic Stewardship (SIP, SITIP, SIMRI, SIAIP, SIMEUP, SIPPS, SICUPP, SIMIT, SIMPE, SIPINF, SIT, SIAATIP, SARNEPI, AIEOP, SIM, SITI, SIF, SIFACT, SITA, SIN).Italian journal of pediatrics · 2025Pooled it
- Antibacterial consumption in four paediatric inpatient facilities in Sri Lanka in 2023: a cross-sectional descriptive study.BMJ open · 2026Article
- Acute Respiratory Infections in Children: A Narrative Perspective on Integrated Primary-Hospital Care in Italy.Children (Basel, Switzerland) · 2026Article
- Appropriateness and Abuse of Antipyretics, Anti-Inflammatory Drugs and Antibiotics in Children and Adults.Antibiotics (Basel, Switzerland) · 2026Review
- Persistent use of broad-spectrum antibiotics for suspected community acquired urinary tract infections in children in Italian primary care settings.Italian journal of pediatrics · 2026Article
- Trajectories of antibiotic prescriptions in Italian children in the first four years of life: a retrospective birth-cohort study.BMC public health · 2026Article
- Long-term public antibiotic awareness campaign significantly reduced inappropriate antibiotic use in pediatric primary care settings.Frontiers in public health · 2026Article
- The Use of Point-of-Care Tests and Multiplex PCR Tests in the Pediatric Emergency Department Reduces Antibiotic Prescription in Patients with Febrile Acute Respiratory Infections.Pathogens (Basel, Switzerland) · 2025Article
- Analysis of antibiotic prescription in upper respiratory tract infections in children 0-4 years of age in primary care. Impact of age and health care setting.European journal of pediatrics · 2025Article
- State of the Art of Antimicrobial and Diagnostic Stewardship in Pediatric Setting.Antibiotics (Basel, Switzerland) · 2025Review
- Appropriateness of antibiotic prescribing in paediatrics: retrospective controlled study assessing a multifaceted intervention in Northern Italy in a 7-year period.BMJ paediatrics open · 2024Article
- Leading reasons for antibiotic prescriptions in pediatric respiratory infections: influence of fever in a primary care setting.Italian journal of pediatrics · 2023Observational
- Retrospective Analysis of the Real-World Use of Topical Antimicrobials in the Paediatric Population with Impetigo in Italy: Focus on the Role of Ozenoxacin 1% Cream.Children (Basel, Switzerland) · 2023Article
- Watchful Waiting in Pediatric Acute Otitis Media: A Real Practice Approach or an Intangible Desideratum?Medicina (Kaunas, Lithuania) · 2023Review
- Assessing the burden of bronchiolitis and lower respiratory tract infections in children ≤24 months of age in Italy, 2012-2019.Frontiers in pediatrics · 2023Article
- Antibiotic Prescription Patterns in the Paediatric Primary Care Setting before and after the COVID-19 Pandemic in Italy: An Analysis Using the AWaRe Metrics.Antibiotics (Basel, Switzerland) · 2022Article
- Reduction in broad-spectrum antimicrobial prescriptions by primary care pediatricians following a multifaceted antimicrobial stewardship program.Frontiers in pediatrics · 2022Article
- Morbidity and Drug Prescribing Pattern in Pediatric Outpatient Department of Kankai Nagar Hospital of Eastern Nepal.Sage open pediatricsArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comprehensive data are needed to monitor antibiotic prescribing and inform stewardship. We aimed to evaluate the current antibiotic prescribing patterns, including treatment switching and prolongation, in the paediatric primary care setting in Italy. This database study assessed antibiotic prescriptions retrieved from Pedianet, a paediatric primary care database, from 1 January 2012 to 31 December 2018. Descriptive analyses were stratified by diagnosis class, calendar year, and children's age. Generalized linear Poisson regression was used to assess variation in the prescriptions. In total, 505,927 antibiotic prescriptions were included. From 2012 to 2018, the number of antibiotics per child decreased significantly by 4% yearly from 0.79 in 2012 to 0.62 in 2018. Amoxicillin prescriptions decreased with increasing children's age, while macrolides and third-generation cephalosporins had the opposite trend. Prescriptions were associated with a diagnosis of upper respiratory infection in 23% of cases, followed by pharyngitis (21%), bronchitis and bronchiolitis (12%), and acute otitis media (12%). Eight percent of treatment episodes were prolonged or switched class, mostly represented by co-amoxiclav, macrolides, and third-generation cephalosporins. Our findings report an overall decrease in antibiotic prescriptions, but pre-schoolers are still receiving more than one antibiotic yearly, and broad-spectrum antibiotics prescription rates remain the highest.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.