Evidence map›Paper›PMID 35052891›Full record

ReviewAntibiotics (Basel, Switzerland)2021

Strategies for Antimicrobial Peptides Immobilization on Surfaces to Prevent Biofilm Growth on Biomedical Devices.

Mathieu Nicolas, Bruno Beito, Marta Oliveira, Maria Tudela Martins, Bruno Gallas, Michèle Salmain, Souhir Boujday, Vincent Humblot

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Mathieu NicolasSorbonne Université, UMR 7197, Laboratoire de Réactivité de Surface, Centre National de la Recherche Scientifique (CNRS), 4 Place Jussieu, F-75005 Paris, France.
Bruno BeitoSorbonne Université, Master de Chimie, Profil MatNanoBio, Faculté des Sciences et Ingénierie of Sorbonne Université, 4 Place Jussieu, F-75005 Paris, France.
Marta OliveiraSorbonne Université, Master de Chimie, Profil MatNanoBio, Faculté des Sciences et Ingénierie of Sorbonne Université, 4 Place Jussieu, F-75005 Paris, France.
Maria Tudela MartinsSorbonne Université, Master de Chimie, Profil MatNanoBio, Faculté des Sciences et Ingénierie of Sorbonne Université, 4 Place Jussieu, F-75005 Paris, France.
Bruno GallasSorbonne Université, Institute of Nanosciences Paris (INSP), Centre National de la Recherche Scientifique (CNRS), 4 Place Jussieu, F-75005 Paris, France.
Michèle SalmainSorbonne Université, Institut Parisien de Chimie Moléculaire (IPCM), Centre National de la Recherche Scientifique (CNRS), 4 Place Jussieu, F-75005 Paris, France.ORCID 0000-0003-3039-5659
Souhir BoujdaySorbonne Université, UMR 7197, Laboratoire de Réactivité de Surface, Centre National de la Recherche Scientifique (CNRS), 4 Place Jussieu, F-75005 Paris, France.ORCID 0000-0002-5500-0951
Vincent HumblotSorbonne Université, UMR 7197, Laboratoire de Réactivité de Surface, Centre National de la Recherche Scientifique (CNRS), 4 Place Jussieu, F-75005 Paris, France.ORCID 0000-0002-6266-3956
Centre National de la Recherche Scientifique · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nosocomial and medical device-induced biofilm infections affect millions of lives and urgently require innovative preventive approaches. These pathologies have led to the development of numerous antimicrobial strategies, an emergent topic involving both natural and synthetic routes, among which some are currently under testing for clinical approval and use. Antimicrobial peptides (AMPs) are ideal candidates for this fight. Therefore, the strategies involving surface functionalization with AMPs to prevent bacterial attachment/biofilms formation have experienced a tremendous development over the last decade. In this review, we describe the different mechanisms of action by which AMPs prevent bacterial adhesion and/or biofilm formation to better address their potential as anti-infective agents. We additionally analyze AMP immobilization techniques on a variety of materials, with a focus on biomedical applications. Furthermore, we summarize the advances made to date regarding the immobilization strategies of AMPs on various surfaces and their ability to prevent the adhesion of various microorganisms. Progress toward the clinical approval of AMPs in antibiotherapy is also reviewed.

Indexed as

AMPantimicrobialbiofilmsbiofunctionalizationimmobilizationpeptide

Identifiers

PMID35052891
PMCPMC8772980
OpenAlexW4200196335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.