Evidence map›Paper›PMID 35052812›Full record

ArticleBiomedicines2022

Postprandial Hyperlipidemia: Association with Inflammation and Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis.

Natalia Mena-Vázquez, Rocío Redondo-Rodríguez, José Rioja, Francisco Gabriel Jimenez-Nuñez, Sara Manrique-Arija, Jose Manuel Lisbona-Montañez, Laura Cano-García, Marta Rojas-Gimenez, Inmaculada Ureña, Pedro Valdivielso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Natalia Mena-VázquezInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.ORCID 0000-0001-6173-2051
Rocío Redondo-RodríguezInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.
José RiojaInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.ORCID 0000-0002-1196-0352
Francisco Gabriel Jimenez-NuñezInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.
Sara Manrique-ArijaInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.ORCID 0000-0003-2284-7846
Jose Manuel Lisbona-MontañezUGC de Reumatología, Hospital Regional Universitario de Málaga, 29009 Malaga, Spain.ORCID 0000-0002-9125-2208
Laura Cano-GarcíaInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.
Marta Rojas-GimenezUGC de Reumatología, Instituto Maimónides de Investigación Biomédica de Cordoba (IMIBIC), Hospital Universitario Reina Sofia, 14004 Cordoba, Spain.ORCID 0000-0001-8290-3542
Inmaculada UreñaInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.
Pedro ValdivielsoInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.ORCID 0000-0003-4458-9833
Antonio Fernández-NebroInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.ORCID 0000-0002-2962-9844
Hospital Regional Universitario de Málaga · ESHospital Clínico Universitario Virgen de la Victoria · ESInstituto de Investigación Biomédica de Málaga · ESInstituto Maimónides de Investigación Biomédica de Córdoba · ES

Funding

Sociedad Española de Reumatología Grant from "Fundación Española de Reumatología" 2018 for nonfunded projects.
6 · The paper itself

Abstract

objectiveTo describe postprandial lipidemia in patients with rheumatoid arthritis (RA) and to analyze its association with subclinical atherosclerosis and inflammatory activity.

methodsObservational study of 80 cases of RA and 80 sex- and age-matched controls. We excluded individuals with dyslipidemia. Postprandial hyperlipidemia (PPHL) was defined as postprandial triglycerides >220 mg/dL and/or postprandial ApoB48 levels >75th percentile (>p75). Plasma lipids, cholesterol, triglycerides, ApoB48, and total ApoB were evaluated at baseline and after a meal. Other variables analyzed included subclinical atherosclerosis (defined as presence of carotid atheromatous plaque), inflammatory activity (disease activity score (DAS28-ESR)), cytokines, apolipoproteins, and physical activity. A multivariate analysis was performed to identify factors associated with PPHL in patients with RA.

resultsA total of 75 patients with RA and 67 healthy controls fulfilled the inclusion criteria. PPHL was more frequent in patients with RA than controls (No. (%), 29 (38.70) vs. 15 (22.40);

conclusionPPHL was more frequent in patients with RA than in controls. PPHL in patients with RA was associated with inflammation and subclinical atherosclerosis.

Indexed as

apolipoprotein B48inflammationpostprandial lipemiarheumatoid arthritissubclinical atherosclerosistriglycerides

Identifiers

PMID35052812
PMCPMC8773280
OpenAlexW4205504462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.