Evidence map›Paper›PMID 35052783›Full record

ArticleBiomedicines2022

NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model.

Matteo Gasparotto, Yuriko Suemi Hernandez Gomez, Daniele Peterle, Alessandro Grinzato, Federica Zen, Giulia Pontarollo, Laura Acquasaliente, Giorgia Scapin, Elisabetta Bergantino, Vincenzo De Filippis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Matteo GasparottoSynthetic Biology and Biotechnology Unit, Department of Biology, University of Padua, 35131 Padua, Italy.ORCID 0000-0003-4933-2578
Yuriko Suemi Hernandez GomezSynthetic Biology and Biotechnology Unit, Department of Biology, University of Padua, 35131 Padua, Italy.
Daniele PeterleDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy.
Alessandro GrinzatoSynthetic Biology and Biotechnology Unit, Department of Biology, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-6307-3053
Federica ZenSynthetic Biology and Biotechnology Unit, Department of Biology, University of Padua, 35131 Padua, Italy.
Giulia PontarolloDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0002-6783-8241
Laura AcquasalienteDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-6495-0871
Giorgia ScapinDepartment of Medicine, Harvard Medical School, Boston, MA 02115, USA.
Elisabetta BergantinoSynthetic Biology and Biotechnology Unit, Department of Biology, University of Padua, 35131 Padua, Italy.ORCID 0000-0002-8028-0676
Vincenzo De FilippisDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-9775-8894
Francesco FilippiniSynthetic Biology and Biotechnology Unit, Department of Biology, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-5672-0726
University of Padua · ITHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homo- and heterophilic binding mediated by the immunoglobulin (Ig)-like repeats of cell adhesion molecules play a pivotal role in cell-cell and cell-extracellular matrix interactions. L1CAM is crucial to neuronal differentiation, in both mature and developing nervous systems, and several studies suggest that its functional interactions are mainly mediated by Ig2-Ig2 binding. X-linked mutations in the human

Indexed as

biomimetic peptideCRASH syndromehomophilic bindingL1CAMneuritogenesisneurodevelopmental disorderneuronal differentiationNOG motifregenerative medicine

Identifiers

PMID35052783
PMCPMC8773197
OpenAlexW4205245401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.