Evidence map›Paper›PMID 35052759›Full record

ArticleBiomedicines2021

Alterations in the Proteome and Phosphoproteome Profiles of Rat Hippocampus after Six Months of Morphine Withdrawal: Comparison with the Forebrain Cortex.

Hana Ujcikova, Adam Eckhardt, Lucie Hejnova, Jiri Novotny, Petr Svoboda

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hana UjcikovaLaboratory of Membrane Receptors, Department of Neurochemistry, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague 4, Czech Republic.ORCID 0000-0003-2588-5784
Adam EckhardtLaboratory of Translational Metabolism, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague 4, Czech Republic.
Lucie HejnovaDepartment of Physiology, Faculty of Science, Charles University, Vinicna 7, 128 43 Prague 2, Czech Republic.
Jiri NovotnyDepartment of Physiology, Faculty of Science, Charles University, Vinicna 7, 128 43 Prague 2, Czech Republic.ORCID 0000-0002-6372-0131
Petr SvobodaLaboratory of Membrane Receptors, Department of Neurochemistry, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague 4, Czech Republic.
Czech Academy of Sciences · CZCharles University · CZ

Funding

Czech Science Foundation 19-03295Sthe Institute of Physiology RVO:67985823
6 · The paper itself

Abstract

The knowledge about proteome changes proceeding during protracted opioid withdrawal is lacking. Therefore, the aim of this work was to analyze the spectrum of altered proteins in the rat hippocampus in comparison with the forebrain cortex after 6-month morphine withdrawal. We utilized 2D electrophoretic workflow (Pro-Q

Indexed as

energy metabolismgel-based proteomicsnLC-MS/MSoxidative stressprotracted morphine withdrawalrat brain cortexrat hippocampus

Identifiers

PMID35052759
PMCPMC8772819
OpenAlexW4206650172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.