Evidence map›Paper›PMID 35052721›Full record

ArticleBiomedicines2021

In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside.

Estefanía Burgos-Morón, Nuria Pastor, Manuel Luis Orta, Julio José Jiménez-Alonso, Carlos Palo-Nieto, Margarita Vega-Holm, José Manuel Vega-Pérez, Fernando Iglesias-Guerra, Santiago Mateos, Miguel López-Lázaro and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Estefanía Burgos-MorónDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0002-6231-190X
Nuria PastorDepartment of Cell Biology, Faculty of Biology, University of Seville, 41012 Seville, Spain.
Manuel Luis OrtaDepartment of Cell Biology, Faculty of Biology, University of Seville, 41012 Seville, Spain.
Julio José Jiménez-AlonsoDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0002-2476-2507
Carlos Palo-NietoDepartment of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Margarita Vega-HolmDepartment of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0003-2197-2004
José Manuel Vega-PérezDepartment of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Fernando Iglesias-GuerraDepartment of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.
Santiago MateosDepartment of Cell Biology, Faculty of Biology, University of Seville, 41012 Seville, Spain.
Miguel López-LázaroDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0003-2794-1647
José Manuel Calderón-MontañoDepartment of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, Spain.ORCID 0000-0001-6845-797X
Universidad de Sevilla · ESUppsala University · SE

Funding

University of Seville VPPI-I.5
6 · The paper itself

Abstract

We recently screened a series of new aziridines β-D-galactopyranoside derivatives for selective anticancer activity and identified 2-methyl-2,3-[

Indexed as

aziridinecancercytotoxiccytotoxicitynucleotide excision repairselectivity

Identifiers

PMID35052721
PMCPMC8773213
OpenAlexW4225476140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.