Evidence map›Paper›PMID 35052715›Full record

ArticleBiomedicines2021

Exosomal microRNA Differential Expression in Plasma of Young Adults with Chronic Mild Traumatic Brain Injury and Healthy Control.

Rany Vorn, Maiko Suarez, Jacob C White, Carina A Martin, Hyung-Suk Kim, Chen Lai, Si-Jung Yun, Jessica M Gill, Hyunhwa Lee

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rany VornNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20814, USA.ORCID 0000-0002-9158-9302
Maiko SuarezSchool of Medicine, University of Nevada, Las Vegas, NV 89102, USA.
Jacob C WhiteCollege of Liberal Arts, University of Nevada, Las Vegas, NV 89154, USA.
Carina A MartinNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20814, USA.ORCID 0000-0002-6239-9817
Hyung-Suk KimNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20814, USA.
Chen LaiNational Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20814, USA.
Si-Jung YunYotta Biomed, LLC, Bethesda, MD 20817, USA.
Jessica M GillSchool of Nursing and Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Hyunhwa LeeSchool of Nursing, University of Nevada, Las Vegas, NV 89154, USA.ORCID 0000-0002-5625-3141
National Institutes of Health · USUniversity of Nevada, Las Vegas · USJohns Hopkins University · US

Funding

American Psychiatric Nurses Association GR009253University of Nevada, Las Vegas 2221-257-554G
6 · The paper itself

Abstract

Chronic mild traumatic brain injury (mTBI) has long-term consequences, such as neurological disability, but its pathophysiological mechanism is unknown. Exosomal microRNAs (exomiRNAs) may be important mediators of molecular and cellular changes involved in persistent symptoms after mTBI. We profiled exosomal microRNAs (exomiRNAs) in plasma from young adults with or without a chronic mTBI to decipher the underlying mechanisms of its long-lasting symptoms after mTBI. We identified 25 significantly dysregulated exomiRNAs in the chronic mTBI group (

Indexed as

exomiRNAexosomemicroRNAmild traumatic brain injury

Identifiers

PMID35052715
PMCPMC8773035
OpenAlexW4200276038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.