Evidence map›Paper›PMID 35052609›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Chemical Composition of Green Pea (

Luigi Castaldo, Luana Izzo, Anna Gaspari, Sonia Lombardi, Yelko Rodríguez-Carrasco, Alfonso Narváez, Michela Grosso, Alberto Ritieni

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Purification of Spent Hop Cone (Antioxidants (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Review
  10. Chemical Profile and Promising Applications ofAntioxidants (Basel, Switzerland) · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. A Comprehensive Review of Pea (Foods (Basel, Switzerland) · 2023
    Review
  18. Agri-Food Wastes as Natural Source of Bioactive Antioxidants.Antioxidants (Basel, Switzerland) · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luigi CastaldoDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0001-6883-9396
Luana IzzoDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0002-8365-9032
Anna GaspariDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0001-7155-8624
Sonia LombardiDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0002-4447-0798
Yelko Rodríguez-CarrascoLaboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Spain.ORCID 0000-0002-6421-218X
Alfonso NarváezDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.
Michela GrossoDepartment of Molecular Medicine and Medical Biotechnology, School of Medicine, University of Naples "Federico II", 5 Sergio Pansini Street, 80131 Naples, Italy.ORCID 0000-0003-1664-1657
Alberto RitieniDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80141 Napoli, Italy.ORCID 0000-0003-0314-8839

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agro-industrial wastes contain a large number of important active compounds which can justify their use as innovative ingredients in nutraceutical products. This study aimed to provide a complete analysis of active molecules, namely (poly)phenols in pea pods water-based extracts, through a UHPLC-Q-Orbitrap HRMS methodology. Data showed that 5-caffeoylquinic acid, epicatechin, and hesperidin were the most relevant (poly)phenols found in the assayed extracts, with a mean value of 59.87, 29.46, and 19.94 mg/100 g, respectively. Furthermore, changes in antioxidant capacity and bioaccessibility of total phenolic compounds (TPC) after the simulated gastrointestinal (GI) process were performed using spectrophotometric assays (FRAP, DPPH, ABTS, and TPC by Folin-Ciocalteu). The acid-resistant capsules (ARC) and the non-acid resistant capsules (NARC) containing the pea pod extract underwent simulated GI digestion. The results suggested that the ARC formulations were able to preserve the active compounds along the simulated GI process, highlighting a higher TPC value and antioxidant capacity than the NARC formulations and the not-encapsulated extracts. Hence, the pea pods water-based extracts could be utilized as a potential alternative source of active compounds, and the use of ARC could represent a suitable nutraceutical formulation to vehiculate the active compounds, protecting the chemical and bioactive properties of (poly)phenols.

Indexed as

bioaccessibilitybioactive compoundsfood waste valorizationnutraceuticalpeapolyphenols

Identifiers

PMID35052609
PMCPMC8772770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.