Evidence map›Paper›PMID 35052580›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis.

Enrica Federti, Alessandro Matte, Veronica Riccardi, Kevin Peikert, Seth L Alper, Adrian Danek, Ruth H Walker, Angela Siciliano, Iana Iatcenko, Andreas Hermann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Yeast as a Model to Find New Drugs and Drug Targets forInternational journal of molecular sciences · 2022
    Review
  7. Redox signaling and metabolism in Alzheimer's disease.Frontiers in aging neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Enrica FedertiDepartment of Medicine, University of Verona AOUI Verona, 37134 Verona, Italy.
Alessandro MatteDepartment of Medicine, University of Verona AOUI Verona, 37134 Verona, Italy.
Veronica RiccardiDepartment of Medicine, University of Verona AOUI Verona, 37134 Verona, Italy.
Kevin PeikertTranslational Neurodegeneration Section "Albrecht-Kossel", Department of Neurology, University Medical Center Rostock, University of Rostock, 18051 Rostock, Germany.ORCID 0000-0002-0845-2453
Seth L AlperBeth Israel Deaconess Medical Center, Departments of Medicine, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0002-6228-2512
Adrian DanekDepartment of Neurology, University Hospital, 80539 Munich, Germany.ORCID 0000-0001-8857-5383
Ruth H WalkerJames J. Peters Veterans Affairs Medical Center, Department of Neurology, Bronx, NY 10468, USA.
Angela SicilianoDepartment of Medicine, University of Verona AOUI Verona, 37134 Verona, Italy.
Iana IatcenkoDepartment of Medicine, University of Verona AOUI Verona, 37134 Verona, Italy.
Andreas HermannTranslational Neurodegeneration Section "Albrecht-Kossel", Department of Neurology, University Medical Center Rostock, University of Rostock, 18051 Rostock, Germany.ORCID 0000-0002-7364-7791
Lucia De FranceschiDepartment of Medicine, University of Verona AOUI Verona, 37134 Verona, Italy.ORCID 0000-0001-7093-777X
University of Verona · ITUniversity of Rostock · DEBeth Israel Deaconess Medical Center · USJames J. Peters VA Medical Center · USMünchen Klinik · DE

Funding

University of Verona FUR
6 · The paper itself

Abstract

The peroxiredoxins (PRXs) constitute a ubiquitous antioxidant. Growing evidence in neurodegenerative disorders such as Parkinson's disease (PD) or Alzheimer's disease (AD) has highlighted a crucial role for PRXs against neuro-oxidation. Chorea-acanthocytosis/

Indexed as

chorea-acanthocytosisLynneuroinflammationnilotiniboxidative stressperoxiredoxin 2peroxiredoxin 5

Identifiers

PMID35052580
PMCPMC8772732
OpenAlexW4200400027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.