Evidence map›Paper›PMID 35052579›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Human Lysyl Oxidase Over-Expression Enhances Baseline Cardiac Oxidative Stress but Does Not Aggravate ROS Generation or Infarct Size Following Myocardial Ischemia-Reperfusion.

Laura Valls-Lacalle, Lídia Puertas-Umbert, Saray Varona, José Martínez-González, Cristina Rodríguez, Antonio Rodríguez-Sinovas

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Role of copper and its complexes in cardiovascular diseases.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  4. Oxidative Stress in Cardiovascular Disease and Comorbidities.Antioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Laura Valls-LacalleCardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.
Lídia Puertas-UmbertInstitut de Recerca del Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.
Saray VaronaCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBER-CV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
José Martínez-GonzálezCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBER-CV), Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-3894-7166
Cristina RodríguezCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBER-CV), Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-6472-5647
Antonio Rodríguez-SinovasCardiovascular Diseases Research Group, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.ORCID 0000-0003-2930-8773
Instituto de Salud Carlos III · ESConsejo Superior de Investigaciones Científicas · ESHospital de Sant Pau · ES

Funding

Agencia de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) 2017-SGR-00333Agencia de Gestió d'Ajuts Universitaris i de Recerca (AGAUR) 2017-SGR-1807Fundació La Marató TV3 2015.3610Instituto de Salud Carlos III PI17/01397Instituto de Salud Carlos III PI18/0919Spanish Ministerio de Ciencia e Innovacion RTI2018-094727-B-100
6 · The paper itself

Abstract

Lysyl oxidase (LOX) is an enzyme critically involved in collagen maturation, whose activity releases H

Indexed as

cardiac remodelinglysyl oxidasereperfusion injury

Identifiers

PMID35052579
PMCPMC8773108
OpenAlexW4200173347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.