Evidence map›Paper›PMID 35052541›Full record

ArticleAntioxidants (Basel, Switzerland)2021

The Effect of Acute Oral Galactose Administration on the Redox System of the Rat Small Intestine.

Jan Homolak, Ana Babic Perhoc, Ana Knezovic, Jelena Osmanovic Barilar, Davor Virag, Mihovil Joja, Melita Salkovic-Petrisic

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Establishing the link between D-mannose and juvenile grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Hybridization altered the gut microbiota of pigs.Frontiers in microbiology · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jan HomolakDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.ORCID 0000-0003-1508-3243
Ana Babic PerhocDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.
Ana KnezovicDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.ORCID 0000-0001-8011-2034
Jelena Osmanovic BarilarDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.
Davor ViragDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.ORCID 0000-0003-3574-7107
Mihovil JojaDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.
Melita Salkovic-PetrisicDepartment of Pharmacology, University of Zagreb School of Medicine, 10 000 Zagreb, Croatia.
University of Zagreb · HR

Funding

Croatian Science Foundation IP-2018-01-8938European Regional Development Fund GA KK01.1.1.01.0007
6 · The paper itself

Abstract

Galactose is a ubiquitous monosaccharide with important yet incompletely understood nutritive and physiological roles. Chronic parenteral d-galactose administration is used for modeling aging-related pathophysiological processes in rodents due to its ability to induce oxidative stress (OS). Conversely, chronic oral d-galactose administration prevents and alleviates cognitive decline in a rat model of sporadic Alzheimer's disease, indicating that galactose may exert beneficial health effects by acting in the gut. The present aim was to explore the acute time-response of intestinal redox homeostasis following oral administration of d-galactose. Male Wistar rats were euthanized at baseline (

Indexed as

galactosegastrointestinal tractoxidative stressredoxredox homeostasis

Identifiers

PMID35052541
PMCPMC8773155
OpenAlexW4225727003

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.