Evidence map›Paper›PMID 35052521›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Relationships between Skin Carotenoid Levels and Metabolic Syndrome.

Yuji Takayanagi, Akira Obana, Shigeki Muto, Ryo Asaoka, Masaki Tanito, Igor V Ermakov, Paul S Bernstein, Werner Gellermann

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Yuji TakayanagiDepartment of Ophthalmology, Faculty of Medicine, Shimane University, Izumo 693-8501, Japan.
Akira ObanaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.ORCID 0000-0001-7930-3618
Shigeki MutoSeirei Center for Health Promotion and Prevention Medicine, Seirei Social Welfare Community, Hamamatsu 430-0906, Japan.
Ryo AsaokaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu 430-8558, Japan.
Masaki TanitoDepartment of Ophthalmology, Faculty of Medicine, Shimane University, Izumo 693-8501, Japan.ORCID 0000-0001-6512-7203
Igor V ErmakovLongevity Link Corporation, Salt Lake City, UT 84108, USA.
Paul S BernsteinDepartment of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.ORCID 0000-0002-4228-7666
Werner GellermannLongevity Link Corporation, Salt Lake City, UT 84108, USA.
Longevity Biotech (United States) · USShimane University · JPHamamatsu University School of Medicine · JPSeirei Hamamatsu General Hospital · JPSeirei Social Welfare Community · JPUniversity of Utah · US

Funding

University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Behrad Noudoost · 2005 to 2026
$14.6M
Biochemistry and Pharmacology of the Macular CarotenoidsR01EY011600 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI BERNSTEIN, PAUL STEVEN · 2004 to 2025
$7.7M
BIOCHEMISTRY AND PHARMACOLOGY OF THE MACULAR CAROTENOIDSR29EY011600 · NEI · UNIVERSITY OF UTAH · PI BERNSTEIN, PAUL STEVEN · 1997 to 2001
$209k
Eye Institute by grants EY11600Japan Agency for Medical Research and Development 18KK0253Japan Science and Technology Agency 20K09784Ministry of Education, Culture, Sports, Science and Technology of Japan 19H01114NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY011600Research to Prevent Blindness EY14800
6 · The paper itself

Abstract

Carotenoids have potential antioxidant and anti-inflammatory effects; their protective roles are of particular interest in the pathogenesis of metabolic syndrome (MetS). The reflection spectroscopy method has been recently developed to noninvasively measure skin carotenoid (SC) levels, which highly correlates with serum concentration of carotenoids. The relationship between SC levels and metabolic syndrome has been investigated. We aimed to identify the differences in patient characteristics and SC levels between participants with and without MetS in a large health examination population. In addition, the relationships between SC levels and various clinical parameters related to MetS were investigated. SC levels were measured using a reflection spectroscopy. A total of 1812 Japanese participants (859 male, 953 female; mean age ± standard deviation (SD), 57.8 ± 11.0 years) comprised the study population, i.e., participants with MetS (

Indexed as

health examination populationmetabolic syndromeoxidative stressskin carotenoidsVeggie Meter

Identifiers

PMID35052521
PMCPMC8772725
OpenAlexW4200414573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.