ArticleAntioxidants (Basel, Switzerland)2021
Oxidative Stress Measurement in Frozen/Thawed Human Sperm: The Protective Role of an In Vitro Treatment with Myo-Inositol.
Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Unraveling the Multi-Omic Landscape of Extracellular Vesicles in Human Seminal Plasma.Biomolecules · 2025Article
- Exploring the effect of skim milk on the membrane stability of frozen-thawed Inner Mongolia cashmere goat sperm based on proteomics.Frontiers in cell and developmental biology · 2025Article
- Antioxidant and anticoagulant properties of myo-inositol determined in an ex vivo studies and gas chromatography analysis.Scientific reports · 2024Article
- Article
- Impact of Seminal Plasma Antioxidants on DNA Fragmentation and Lipid Peroxidation of Frozen-Thawed Horse Sperm.Antioxidants (Basel, Switzerland) · 2024Article
- Impact of the Antioxidant Hydroxytyrosol on the Quality of Post-Thawed Stallion Semen.Veterinary medicine international · 2024Article
- Exposure to Cumulus Cell Secretome Improves Sperm Function: New Perspectives for Sperm Selection In Vitro.Cells · 2023Article
- Antioxidant Effects of Myo-Inositol Improve the Function and Fertility of Cryopreserved Boar Semen.Antioxidants (Basel, Switzerland) · 2023Article
- Human Sperm as an In Vitro Model to Assess the Efficacy of Antioxidant Supplements during Sperm Handling: A Narrative Review.Antioxidants (Basel, Switzerland) · 2023Review
- Role of antioxidants in fertility preservation of sperm - A narrative review.Animal bioscience · 2023Article
- Sperm cryopreservation for impaired spermatogenesis.Reproduction & fertility · 2023Article
- Myo-inositol improves the viability of boar sperm during liquid storage.Frontiers in veterinary science · 2023Article
- Article
- Cellular and Molecular Mechanisms of In Vivo and In Vitro SARS-CoV-2 Infection: A Lesson from Human Sperm.Cells · 2022Article
- Antioxidant Activity and Oxidative Stress-Oriented Apoptosis Pathway in Saccharides Supplemented Cryopreserved Sperm of Pacific Abalone,Antioxidants (Basel, Switzerland) · 2022Article
- Antioxidants and Male Infertility.Antioxidants (Basel, Switzerland) · 2022Article
- Positive Effect of a New Combination of Antioxidants and Natural Hormone Stimulants for the Treatment of Oligoasthenoteratozoospermia.Journal of clinical medicine · 2022Article
- Liang-Ge decoction ameliorates acute lung injury in septic model rats through reducing inflammatory response, oxidative stress, apoptosis, and modulating host metabolism.Frontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite its widespread use, sperm cryopreservation induces serious detrimental alterations in sperm function; indeed, it is commonly associated with decreased sperm viability and motility, and DNA fragmentation. Mechanisms of human sperm cryodamage are thought to be multifactorial, but oxidative stress seems to have a prominent role. A huge amount of data supported the cryoprotective effect of different antioxidants able to minimize the detrimental effects of reactive oxygen species (ROS) and improve the quality of spermatozoa. Among others, myo-inositol is one of the most powerful and has been reported to be effective in improving sperm quality and motility when used both in vivo and in vitro. This study aimed to determine the in vitro impact of myo-inositol in ameliorating sperm oxidative status during sperm cryopreservation. In particular, we demonstrated a significant improvement of sperm parameters (vitality and motility) when myo-inositol was added after sperm thawing (
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