Evidence map›Paper›PMID 35052510›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Glutathione Is Required for the Early Alert Response and Subsequent Acclimation in Cadmium-Exposed

Jana Deckers, Sophie Hendrix, Els Prinsen, Jaco Vangronsveld, Ann Cuypers

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jana DeckersCentre for Environmental Sciences, Hasselt University, Agoralaan Building D, 3590 Diepenbeek, Belgium.ORCID 0000-0002-4780-3025
Sophie HendrixCentre for Environmental Sciences, Hasselt University, Agoralaan Building D, 3590 Diepenbeek, Belgium.ORCID 0000-0001-7436-0234
Els PrinsenDepartment of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerpen, Belgium.ORCID 0000-0003-4320-1585
Jaco VangronsveldCentre for Environmental Sciences, Hasselt University, Agoralaan Building D, 3590 Diepenbeek, Belgium.ORCID 0000-0003-4423-8363
Ann CuypersCentre for Environmental Sciences, Hasselt University, Agoralaan Building D, 3590 Diepenbeek, Belgium.ORCID 0000-0002-0171-0245
Hasselt University · BEUniversity of Antwerp · BEUniversity of Bonn · DE

Funding

Research Foundation - Flanders 1182220NResearch Foundation - Flanders G0B6716NResearch Foundation - Flanders G0C7518N
6 · The paper itself

Abstract

Pollution by cadmium (Cd) is a worldwide problem, posing risks to human health and impacting crop yield and quality. Cadmium-induced phytotoxicity arises from an imbalance between antioxidants and pro-oxidants in favour of the latter. The Cd-induced depletion of the major antioxidant glutathione (GSH) strongly contributes to this imbalance. Rather than being merely an adverse effect of Cd exposure, the rapid depletion of root GSH levels was proposed to serve as an alert response. This alarm phase is crucial for an optimal stress response, which defines acclimation later on. To obtain a better understanding on the importance of GSH in the course of these responses and how these are defined by the rapid GSH depletion, analyses were performed in the GSH-deficient

Indexed as

1-aminocyclopropane-1-carboxylic acidArabidopsis thalianacadmiumcadmium-sensitive 2-1 mutantethyleneglutathionehydrogen peroxideoxidative challenge

Identifiers

PMID35052510
PMCPMC8773091
OpenAlexW4200510901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.