Evidence map›Paper›PMID 35052395›Full record

ArticleGenes2021

Associations of Single-Nucleotide Polymorphisms in Slovenian Patients with Acute Central Serous Chorioretinopathy.

Peter Kiraly, Andrej Zupan, Alenka Matjašič, Polona Jaki Mekjavić

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Peter KiralyEye Hospital, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Andrej ZupanInstitute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-3394-7690
Alenka MatjašičInstitute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Polona Jaki MekjavićEye Hospital, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-1949-4525
University of Ljubljana · SILjubljana University Medical Centre · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central serous chorioretinopathy (CSC) is a chorioretinal disease that usually affects the middle-aged population and is characterised by a thickened choroid, retinal pigment epithelium detachment, and subretinal fluid with a tendency towards spontaneous resolution. We investigated 13 single-nucleotide polymorphisms (SNPs) in 50 Slovenian acute CSC patients and 71 healthy controls in Complement Factor H (CFH), Nuclear Receptor Subfamily 3 Group C Member 2 (NR3C2), Cadherin 5 (CDH5) Age-Related Maculopathy Susceptibility 2 (ARMS2), TNF Receptor Superfamily Member 10a (TNFRSF10A), collagen IV alpha 3 (COL4A3) and collagen IV alpha 4 (COL4A4) genes using high-resolution melt analysis. Statistical calculations revealed significant differences in genotype frequencies for CFH rs1329428 (

Indexed as

Polymorphism, Single NucleotideAdultAntigens, CDBiomarkersCadherin 5CadherinsCase-Control StudiesCentral Serous ChorioretinopathyComplement Factor HFemaleFluorescein AngiographyFollow-Up StudiesGenetic Association StudiesHumansMaleMiddle AgedAntigens, CDBiomarkersCadherin 5CadherinsCFH protein, humanComplement Factor HReceptors, TNF-Related Apoptosis-Inducing LigandTNFRSF10A protein, humanCDH5central serous chorioretinopathyCFHCOL4A3COL4A4collagenCSCgenotype–phenotype correlationrs1329428TNFRSF10A

Identifiers

PMID35052395
PMCPMC8774639
OpenAlexW4205466645

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.