Evidence map›Paper›PMID 35052391›Full record

ArticleGenes2021

Heterozygous

Taimoor I Sheikh, Ricardo Harripaul, Nasim Vasli, Majid Ghadami, Susan L Santangelo, Muhammad Ayub, Roksana Sasanfar, John B Vincent

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Taimoor I SheikhMolecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.
Ricardo HarripaulMolecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.
Nasim VasliDepartment of Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.
Majid GhadamiDepartment of Educational Sciences, Farhangian University, Tehran 19989-63341, Iran.
Susan L SantangeloCenter for Psychiatric Research, Maine Medical Center Research Institute, Portland, ME 04101, USA.
Muhammad AyubDepartment of Psychiatry, Queen's University, Kingston, ON K7L 7X3, Canada.
Roksana SasanfarDepartment of Psychiatry, Harvard Medical School, Boston, MA 02215, USA.
John B VincentMolecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON M5T 1R8, Canada.ORCID 0000-0003-0692-2519
Centre for Addiction and Mental Health · CAFarhangian University · IRHarvard University · USHospital for Sick Children · CAQueen's University · CATufts University · US

Funding

CIHR MOP-102758CIHR PJT-156402Wellcome Trust
6 · The paper itself

Abstract

Nucleolin (NCL/C23; OMIM: 164035) is a major nucleolar protein that plays a critical role in multiple processes, including ribosome assembly and maturation, chromatin decondensation, and pre-rRNA transcription. Due to its diverse functions, nucleolin has frequently been implicated in pathological processes, including cancer and viral infection. We recently identified a

Indexed as

HeterozygoteMutationAutism Spectrum DisorderCell NucleolusHEK293 CellsHumansMaleNucleolinPhosphoproteinsRNA-Binding ProteinsNucleolinPhosphoproteinsRNA-Binding Proteinsautism spectrum disorder (ASD)C23GAR domainnucleolar localization signalnucleolin

Identifiers

PMID35052391
PMCPMC8774667
OpenAlexW4200075642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.