Evidence map›Paper›PMID 35052377›Full record

ArticleGenes2021

Somatic Reversion of a Novel

Yujuan Hou, Hans Peter Gratz, Guillermo Ureña-Bailén, Paul G Gratz, Karin Schilbach-Stückle, Tina Renno, Derya Güngör, Daniel A Mader, Elke Malenke, Justin S Antony and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Monogenic etiologies of persistent human papillomavirus infections: A comprehensive systematic review.Genetics in medicine : official journal of the American College of Medical Genetics · 2024
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. HemizygousThe application of clinical genetics · 2025
    Article
  9. Article
  10. Article
  11. NovelCentral-European journal of immunology · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yujuan HouDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Hans Peter GratzDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Guillermo Ureña-BailénDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Paul G GratzDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Karin Schilbach-StückleDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-8041-055X
Tina RennoDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Derya GüngörDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Daniel A MaderDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-8527-4278
Elke MalenkeDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Justin S AntonyDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Rupert HandgretingerDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.
Markus MezgerDepartment of Pediatrics I, Hematology and Oncology, University Children's Hospital, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-0211-2343
University Children's Hospital Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations of the

Indexed as

AdultCD8-Positive T-LymphocytesCell ProliferationHumansInterleukin Receptor Common gamma SubunitMaleMutationPhenotypeX-Linked Combined Immunodeficiency DiseasesYoung AdultIL2RG protein, humanInterleukin Receptor Common gamma Subunitatypical X-SCIDhypomorphic mutationIL-2RGimmunodeficiencysomatic reversionγC

Identifiers

PMID35052377
PMCPMC8774591
OpenAlexW4200441667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.