Evidence map›Paper›PMID 35052344›Full record

ArticleGenes2021

Genotype Score for Iron Status Is Associated with Muscle Fiber Composition in Women.

Mizuki Takaragawa, Takuro Tobina, Keisuke Shiose, Ryo Kakigi, Takamasa Tsuzuki, Noriko Ichinoseki-Sekine, Hiroshi Kumagai, Hirofumi Zempo, Eri Miyamoto-Mikami, Hiroyuki Kobayashi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Association of theBiology of sport · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Mizuki TakaragawaGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.
Takuro TobinaFaculty of Nursing and Nutrition, University of Nagasaki, Nagasaki 851-2195, Japan.
Keisuke ShioseFaculty of Education, University of Miyazaki, Miyazaki 889-2192, Japan.ORCID 0000-0003-1089-9593
Ryo KakigiFaculty of Management & Information Science, Josai International University, Chiba 283-8555, Japan.
Takamasa TsuzukiFaculty of Pharmacy, Meijo University, Aichi 468-8503, Japan.
Noriko Ichinoseki-SekineGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.ORCID 0000-0002-0467-3312
Hiroshi KumagaiGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.
Hirofumi ZempoFaculty of Health and Nutrition, Tokyo Seiei College, Tokyo 124-8530, Japan.ORCID 0000-0003-2248-8580
Eri Miyamoto-MikamiGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.
Hiroyuki KobayashiGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.ORCID 0000-0001-8377-0091
Hisashi NaitoGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.ORCID 0000-0002-0522-9512
Noriyuki FukuGraduate School of Health and Sports Science, Juntendo University, Chiba 270-1695, Japan.ORCID 0000-0001-7792-5835
Juntendo University · JPJosai International University · JPMeijo University · JPThe Open University of Japan · JPTokyo Seiei College · JPUniversity of Miyazaki · JPUniversity of Nagasaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human muscle fiber composition is heterogeneous and mainly determined by genetic factors. A previous study reported that experimentally induced iron deficiency in rats increases the proportion of fast-twitch muscle fibers. Iron status has been reported to be affected by genetic factors. As the

Indexed as

GenotypeAdolescentAdultFemaleHumansIronJapanMajor Histocompatibility ComplexMaleMembrane ProteinsMuscle Fibers, SkeletalMyosin Heavy ChainsPolymorphism, GeneticSerine EndopeptidasesYoung AdultIronMembrane ProteinsMyosin Heavy ChainsSerine EndopeptidasesTMPRSS6 protein, humananemiagenetic polymorphismHFEhomeostatic iron regulator proteiniron deficiencymatriptase 2myosin heavy chainskeletal muscleTMPRSS6transmembrane serine protease 6

Identifiers

PMID35052344
PMCPMC8775127
OpenAlexW4200192648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.