Evidence map›Paper›PMID 35051899›Full record

ArticleMedical image analysis2022

Global-Local attention network with multi-task uncertainty loss for abnormal lymph node detection in MR images.

Shuai Wang, Yingying Zhu, Sungwon Lee, Daniel C Elton, Thomas C Shen, Youbao Tang, Yifan Peng, Zhiyong Lu, Ronald M Summers

Open access · greenAbstract read
In one paragraph

Article in Medical image analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. [Detection of neurofibroma combining radiomics and ensemble learning].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  2. Article
  3. Review
  4. Segmentation of mediastinal lymph nodes in CT with anatomical priors.International journal of computer assisted radiology and surgery · 2024
    Article
  5. Detection of abdominopelvic lymph nodes in multi-parametric MRI.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2024
    Article
  6. Universal detection and segmentation of lymph nodes in multi-parametric MRI.International journal of computer assisted radiology and surgery · 2024
    Article
  7. Universal lymph node detection in T2 MRI using neural networks.International journal of computer assisted radiology and surgery · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shuai WangImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA; School of Mechanical, Electrical and Information Engineering, Shandong University, Weihai 264209, PR China. Electronic address: shuaiwang.tai@gmail.com.
Yingying ZhuImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA.
Sungwon LeeImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA.
Daniel C EltonImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA.
Thomas C ShenImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA.
Youbao TangImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA.
Yifan PengNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Zhiyong LuNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Ronald M SummersImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD 20892, USA.
National Institutes of Health Clinical Center · USNational Institutes of Health · US

Funding

Machine learning for medical imaging: automated disease diagnosis and prognosisZIALM010021 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2022 to 2025
$4.1M
A framework to enhance radiology structured report by invoking NLP and DL: Models and ApplicationsR00LM013001 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI PENG, YIFAN · 2020 to 2022
$710k
Computer Aided Detection for Radiologic ImagesZ01CL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2003 to 2008
$41k
Computer Aided Detection for Radiologic ImagesZIACL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2009 to 2025
$0k
Intramural NIH HHS Z01 CL040004NLM NIH HHS R00 LM013001
6 · The paper itself

Abstract

Accurate and reliable detection of abnormal lymph nodes in magnetic resonance (MR) images is very helpful for the diagnosis and treatment of numerous diseases. However, it is still a challenging task due to similar appearances between abnormal lymph nodes and other tissues. In this paper, we propose a novel network based on an improved Mask R-CNN framework for the detection of abnormal lymph nodes in MR images. Instead of laboriously collecting large-scale pixel-wise annotated training data, pseudo masks generated from RECIST bookmarks on hand are utilized as the supervision. Different from the standard Mask R-CNN architecture, there are two main innovations in our proposed network: 1) global-local attention which encodes the global and local scale context for detection and utilizes the channel attention mechanism to extract more discriminative features and 2) multi-task uncertainty loss which adaptively weights multiple objective loss functions based on the uncertainty of each task to automatically search the optimal solution. For the experiments, we built a new abnormal lymph node dataset with 821 RECIST bookmarks of 41 different types of abnormal abdominal lymph nodes from 584 different patients. The experimental results showed the superior performance of our algorithm over compared state-of-the-art approaches.

Indexed as

Lymph NodesMagnetic Resonance ImagingAlgorithmsHumansUncertaintyDeep learningImage detectionLymph nodeMagnetic resonance imaging

Identifiers

PMID35051899
PMCPMC8988884
OpenAlexW4206370803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.