Evidence map›Paper›PMID 35051070›Full record

ArticleToxics2022

The Carcinogenic Properties of Overlooked yet Prevalent Polycyclic Aromatic Hydrocarbons in Human Lung Epithelial Cells.

Alison K Bauer, Katelyn J Siegrist, Melanie Wolff, Lindsey Nield, Thomas Brüning, Brad L Upham, Heiko U Käfferlein, Sabine Plöttner

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Indoor air pollution and airway health.The Journal of allergy and clinical immunology · 2024
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Alison K BauerDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0003-4477-9899
Katelyn J SiegristDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Melanie WolffInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA), 44789 Bochum, Germany.
Lindsey NieldDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Thomas BrüningInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA), 44789 Bochum, Germany.
Brad L UphamDepartment of Pediatrics and Human Development, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-4905-9145
Heiko U KäfferleinInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA), 44789 Bochum, Germany.ORCID 0000-0001-5150-4979
Sabine PlöttnerInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA), 44789 Bochum, Germany.ORCID 0000-0002-6004-0069
Institute for Prevention and Occupational Medicine · DEColorado School of Public Health · USMichigan State University · US

Funding

Understudied polycyclic aromatic hydrocarbons involved in pulmonary inflamationR15ES024893 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI BAUER, ALISON K · 2015 to 2015
$458k
Deutsche Gesetzliche Unfallversicherung Intramural research programNIEHS NIH HHS R15ES024893
6 · The paper itself

Abstract

The WHO classified air pollution as a human lung carcinogen and polycyclic aromatic hydrocarbons (PAHs) are components of both indoor (e.g., tobacco smoke and cookstoves) and outdoor (e.g., wildfires and industrial and vehicle emissions) air pollution, thus a human health concern. However, few studies have evaluated the adverse effects of low molecular weight (LMW) PAHs, the most abundant PAHs in the environment. We hypothesized that LMW PAHs combined with the carcinogenic PAH benzo[

Indexed as

1-methylanthracenebenzo[a]pyreneco-carcinogenicepithelial cellsfluoranthenegap junctionslungmicronucleipolycyclic aromatic hydrocarbons

Identifiers

PMID35051070
PMCPMC8779510
OpenAlexW4206439264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.