Evidence map›Paper›PMID 35051060›Full record

ArticleToxics2022

Accumulation, Depuration, and Biological Effects of Polystyrene Microplastic Spheres and Adsorbed Cadmium and Benzo(a)pyrene on the Mussel

Rebecca von Hellfeld, María Zarzuelo, Beñat Zaldibar, Miren P Cajaraville, Amaia Orbea

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 36 citations in OpenAlex.

  1. The Opposite Roles of Benzo[Environment & health (Washington, D.C.) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Exposure ofAnimals : an open access journal from MDPI · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Rebecca von HellfeldCBET Research Group, Department of Zoology and Animal Cell Biology, Biotechnology PiE and Science and Technology Faculty, Research Centre for Experimental Marine Biology, University of the Basque Country (UPV/EHU), Sarriena z/g, 48940 Leioa, Basque Country, Spain.
María ZarzueloCBET Research Group, Department of Zoology and Animal Cell Biology, Biotechnology PiE and Science and Technology Faculty, Research Centre for Experimental Marine Biology, University of the Basque Country (UPV/EHU), Sarriena z/g, 48940 Leioa, Basque Country, Spain.
Beñat ZaldibarCBET Research Group, Department of Zoology and Animal Cell Biology, Biotechnology PiE and Science and Technology Faculty, Research Centre for Experimental Marine Biology, University of the Basque Country (UPV/EHU), Sarriena z/g, 48940 Leioa, Basque Country, Spain.
Miren P CajaravilleCBET Research Group, Department of Zoology and Animal Cell Biology, Biotechnology PiE and Science and Technology Faculty, Research Centre for Experimental Marine Biology, University of the Basque Country (UPV/EHU), Sarriena z/g, 48940 Leioa, Basque Country, Spain.
Amaia OrbeaCBET Research Group, Department of Zoology and Animal Cell Biology, Biotechnology PiE and Science and Technology Faculty, Research Centre for Experimental Marine Biology, University of the Basque Country (UPV/EHU), Sarriena z/g, 48940 Leioa, Basque Country, Spain.ORCID 0000-0002-0229-4482
University of the Basque Country · ES

Funding

Basque Government IT810-13 and IT302-19EU-JRC CAS6 project CAS Project 30602Spanish Ministry of Economy and Competitiveness CTM2016-81130-RUniversity of the Basque Country (UPV/EHU) VRI grant PLASTOX
6 · The paper itself

Abstract

Filter feeders are target species for microplastic (MP) pollution, as particles can accumulate in the digestive system, disturbing feeding processes and becoming internalized in tissues. MPs may also carry pathogens or pollutants present in the environment. This work assessed the influence of polystyrene (PS) MP size and concentration on accumulation and depuration time and the role of MPs as vectors for metallic (Cd) and organic (benzo(a)pyrene, BaP) pollutants. One-day exposure to pristine MPs induced a concentration-dependent accumulation in the digestive gland (in the stomach and duct lumen), and after 3-day depuration, 45 µm MPs appeared between gill filaments, while 4.5 µm MPs also occurred within gill filaments. After 3-day exposure to contaminated 4.5 µm MPs, mussels showed increased BaP levels whilst Cd accumulation did not occur. Here, PS showed higher affinity to BaP than to Cd. Three-day exposure to pristine or contaminated MPs did not provoke significant alterations in antioxidant and peroxisomal enzyme activities in the gills and digestive gland nor in lysosomal membrane stability. Exposure to dissolved contaminants and to MP-BaP caused histological alterations in the digestive gland. In conclusion, these short-term studies suggest that MPs are ingested and internalized in a size-dependent manner and act as carriers of the persistent organic pollutant BaP.

Indexed as

benzo(a)pyrenecadmiummusselspolystyrene microplasticssize-dependent uptakevectors

Identifiers

PMID35051060
PMCPMC8780594
OpenAlexW4205642327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.